摘要
目的探讨硒酵母联合左甲状腺素钠对甲减患者血脂代谢指标、甲状腺功能及预后的影响。方法选取2018年8月-2019年8月伊犁友谊医院门诊收治的甲减患者82例,按随机数字表法分为两组,各41例。对照组采用左甲状腺素钠治疗,实验组在对照组基础上联合硒酵母治疗,比较两组血脂代谢指标、甲状腺功能指标及不良反应。结果实验组治疗后TC、TG、LDL-C低于对照组,FT3高于对照组,TPOAb、TSH低于对照组,差异有统计学意义(P <0.05);两组均无严重不良反应。结论硒酵母与左甲状腺素钠联合应用于甲减患者中效果显著,可有效控制血脂代谢指标,改善甲状腺功能,且不良反应少,安全可靠。
Objective To investigate the effects of selenium yeast combined with levothyroxine sodium on blood lipid metabolism index, thyroid function and prognosis in patients with hypothyroidism. Methods 82 patients with hypothyroidism admitted to the Friendship Hospital of Ili from November 2018 to November 2019 were enrolled, they were divided into two groups according to the random number table method, 41 cases each. The control group was treated with levothyroxine sodium. The observation group was treated with selenium yeast on the basis of the control group. The blood lipid metabolism index, thyroid function index and adverse reactions were compared between the two groups. Results After treatment, the TC, TG and LDL-C in the observation group were lower than that of the control group, FT3 was higher than that of the control group, TPOAb and TSH were lower than that of the control group, and the incidence of adverse reactions was lower than that of the control group(P < 0.05). Conclusions Selenium yeast combined with levothyroxine sodium is effective in the treatment of hypothyroidism patients, which can effectively control blood lipid metabolism indicators, reduce the incidence of adverse reactions.
作者
孟柳
MENG Liu(Department of Endocrinology,Friendship Hospital of Hi,Hi,Xinjiang 835000,China)
出处
《新疆医学》
2020年第8期842-844,共3页
Xinjiang Medical Journal
