摘要
目的食管癌是一种恶性肿瘤,死亡率高,预后较差,其发病率、死亡率和组织病理学特征因地理位置的不同而存在差异。本研究拟探讨河南省林州市食管癌死亡特征及变化趋势。方法根据河南省林州市肿瘤登记处2005-2016年的死亡资料,计算死亡率和标化死亡率。采用Joinpoint回归估计死亡率的年度变化百分比(annual percentage change,APC),分析食管癌死亡率的变化趋势。结果2005-2016年河南省林州市食管癌死亡率总体呈下降趋势,2005年食管癌中标死亡率为70.09/10万,世标死亡率70.67/10万,到2016年已分别降低到42.28/10万和42.02/10万。男性死亡率2005-2016年每年下降0.76%,女性死亡率2005-2016年每年下降1.78%,差异均无统计学意义,P>0.05,男女死亡率APC比较差异有统计学意义,P<0.001。中标率和世标率男性2005-2016年每年分别下降3.31%和3.38%,女性2005-2016年每年分别下降6.41%和7.27%,其中女性死亡率变化有统计学意义,P<0.05。结论2005-2016年河南省林州市食管癌的死亡率总体呈下降趋势,女性下降幅度大于男性。
OBJECTIVE The Esophageal cancer is a malignant tumor,with high mortality and poor prognosis.Its morbidity,mortality and histopathological characteristics vary significantly with geographical location.This study aimed to detect the death characteristics and trend of esophageal cancer in Linzhou,Henan.METHODS According to the mortality data of esophageal cancer of the Central Cancer Registry in Linzhou,Henan,from 2005 to 2016,esophageal cancer mortality and the mortality of standardized population age structural adjustment were calculated.Joinpoint regression was performed to obtain the annual percentage changes(APC)in mortality and the mortality trend of esophageal cancer to analyze the change.RESULTS The mortality of esophageal cancer was generally declining in Linzhou,Henan Province,2005-2016.In 2005,the age-standardized mortality rate by Chinese standard population and by world standard population were70.09/10 million and 70.67/10 million,respectively.In 2016,they had been reduced to 42.28/10 million and 42.02/10 million,respectively.There was a decreasing trend of mortality rate with an average annual percentage change(AAPC)of 0.76%in men and 1.78%in women,2005-2016,respectively.There was a decreasing trend of mortality rate by Chinese standard population and by world standard population with an AAPC of 3.31%and 3.38%in men respectively from2005 to 2016.There was a decreasing trend of mortality rate by Chinese standard population and by world standard population with an AAPC of 6.41% and 7.27%in women respectively from 2005 to 2016.There was significant difference in the declining trend of the standardized mortality rate of esophageal cancer(P<0.05).CONCLUSION The overall mortality rate of esophageal cancer is declining,and the decline of women is greater than that of men in Linzhou,Henan Province,2005-2016.
作者
李变云
付方现
王振海
臧钊平
于晓东
LI Bian-yun;FU Fang-xian;WANG Zhen-hai;ZANG Zhao-ping;YU Xiao-dong(Department of Epidemiology,Linzhou Tumor Hospital,Linzhou 456550,P.R.China;School of Public Health,Capital Medical University,Beijing 100069,P.R.China)
出处
《中华肿瘤防治杂志》
CAS
北大核心
2020年第18期1443-1447,共5页
Chinese Journal of Cancer Prevention and Treatment
关键词
食管癌
死亡率
趋势
林州市
esophageal cancer
mortality
trend
Linzhou City
