摘要
苏铁是我国的一级保护植物,具有很高的药用价值,早在清朝时期就已记载开始利用苏铁来治疗疾病。早期对苏铁的研究主要集中于分类、保护和育种,近几年来,人们开始研究苏铁植物的主要化学成分、化学结构和药理作用,为苏铁植物的进一步开发利用打下了坚实的理论基础。苏铁中主要含有能用于肿瘤治疗的双黄酮类化合物,目前在苏铁植物中研究发现的双黄酮化合物大多是穗花杉双黄酮和扁柏双黄酮的衍生物。苏铁提取物除了具有抗肿瘤活性之外,还具有抑菌、抗氧化和增强免疫力等药理活性。
Cycas revolute Thunb is a first class protected plant in China and has high medicinal value.As early as the Qing dynasty,it was recorded that Cycas was use to treat disease.Early research on Cycas mainly focused on classification,protection and breeding.In recent years,people began to study the main chemical constituents,chemical structure and pharmacological effects of Cycas,which laid a solid theoretical foundation for the further development and utilization of Cycas.At present,most of amentoflavone derivatives and hinokiflavone derivatives found in Cycas have the therapeutic effect on tumor.In addition to the antitumor activity,the extracts of Cycas also have antibacterial,antioxidant and immunological activities.
作者
刘颖杰
黄玉玲
许颖
付纪源
LIU Ying-jie;HUANG Yu-ling;XU Ying;FU Ji-yuan(Engineering Research Center of Natural Anticancer Drugs,Ministry of Education,College of Pharmacy,Harbin University of Commerce,Harbin 150076,China;Engineering Research Center for Medicine,College of Pharmacy,Harbin University of Commerce,Harbin 150076,China)
出处
《中国药学杂志》
CAS
CSCD
北大核心
2020年第18期1492-1498,共7页
Chinese Pharmaceutical Journal
基金
黑龙江省自然基金联合引导项目资助(LH2020H068,LH2020H070)
黑龙江省自然科学基金项目资助(H2017001)
黑龙江省青年创新人才项目资助(UNPYSCT-2018139)
哈尔滨商业大学创新人才项目资助(2019CX38)。
关键词
苏铁
化学成分
药理活性
双黄酮
苏铁苷
Cycas revolute Thunb
chemical constituents
pharmacological activity
biflavone
cycasin
