颅内动脉瘤介入治疗中应用替罗非班防治血栓形成的研究进展被引量：5

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摘要目前,颅内动脉瘤主要有两种治疗方法:开颅夹闭术和血管介入治疗[1]。栓塞术中由于各种原因常易导致血栓形成或血栓栓塞等并发症,发生率在2%~15%,部分病人可能死亡或残留永久神经功能障碍[2,3]。目前,血栓栓塞的治疗方法主要包括静脉注射肝素、静脉注射阿司匹林、使用尿激酶或组织纤溶酶原激活剂进行溶栓,以及机械血栓切除术[4]。这些方法都伴随再出血、血栓移位的风险。糖蛋白Ⅱb/Ⅲa受体拮抗剂替罗非班可有效解决上述难题。本文就替罗非班治疗颅内动脉瘤栓塞术后血栓栓塞的研究进展进行综述。

作者李雪源(综述) 冯雷(审校)

机构地区济宁医学院临床医学院济宁市第一人民医院神经外科

出处《中国临床神经外科杂志》 2020年第10期726-727,730,共3页 Chinese Journal of Clinical Neurosurgery

关键词颅内动脉瘤介入治疗血栓形成替罗非班

分类号 R743.9 [医药卫生—神经病学与精神病学] R815.2 [医药卫生—临床医学]

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