摘要
神经突起生长导向因子-1(NT-1)是一种在神经系统里高度表达的层状蛋白,通过与其受体结合参与中枢神经系统的发育及血管形成、炎症反应等过程。本文就近年来NT-1在神经系统疾病、心血管疾病、糖尿病并发症的治疗及肿瘤的发生发展中作用的研究进行了综述,以期为相关疾病治疗提供新思路。
Netrin-1(NT-1)is a kind of laminin highly expressed in nervous system.It participates in the growth of the central nervous system,angiogenesis and inflammation etc.by binding with its receptors.The present article made a review on related researches about role of NT-1 in the treatment of nervous system diseases,cardiovascular diseases and diabetes complications and occurrence and development of tumor in recent years,aiming at providing new thinking for the treatment of related diseases.
作者
常小双
孟令波
CHANG Xiao-shuang;MENG Ling-bo(Department of Cardiology,Second Affiliated Hospital of Harbin Medical University,Harbin,Heilongjiang,150001,China)
出处
《心血管康复医学杂志》
CAS
2020年第5期635-637,共3页
Chinese Journal of Cardiovascular Rehabilitation Medicine
关键词
神经系统疾病
心血管疾病
糖尿病并发症
Nervous system diseases
Cardiovascular diseases
Diabetes complications
