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微小RNA在肝细胞肝癌中的作用研究进展 被引量:2

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摘要 肝细胞肝癌是一种高病死率的原发性肝癌,目前的诊断和治疗方法具有局限性。研究发现,微小RNA(miRNA)参与生物个体发育、细胞增殖与分化、肿瘤细胞的发生发展等多种病理过程,并调控致癌基因与抑癌基因的表达。大量研究表明,miRNAs在肝细胞肝癌中异常表达,其可能成为诊断肝细胞肝癌新的生物标志物及治疗靶点。本文对近年来miRNAs在肝细胞肝癌中的研究进展进行综述。
出处 《新乡医学院学报》 CAS 2020年第9期893-896,共4页 Journal of Xinxiang Medical University
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