摘要
脂蛋白相关磷脂酶A2(Lp-PLA2)是一种新型炎症物质,已有研究表明Lp-PLA2与动脉粥样硬化有关,进一步导致心脑血管病的发生。本文主要就近些年来Lp-PLA2与急性脑梗死关系的研究进展进行综述,主要包括Lp-PLA2的生理、生化性质,Lp-PLA2与动脉粥样硬化及急性脑梗死的临床研究,从脑梗死的发生、发展及预后等几个方面进行阐述,并简述了目前遇到的问题。
Lipoprotein associated phospholipase A2(Lp-PLA2)is a new type of inflammatory mediator.Studies have shown that Lp-PLA2 is related to atherosclerosis,which further leads to the occurrence of cardiovascular disease.This article mainly summarizes the research progress of the relationship between Lp-PLA2 and acute cerebral infarction in recent years,including the physiological and biochemical properties of Lp-PLA2,and the clinical studies of the relationship of Lp-PLA2 with atherosclerosis and acute cerebral infarction.
作者
马岩
刘艳杰
MA Yan;LIU Yanjie(Postgraduate of Grade 2018,Shenyang Medical College,Shenyang 110034,China;Department of Neurology,The Central Hospital Affiliated to Shenyang Medical College)
出处
《沈阳医学院学报》
2020年第5期483-485,505,共4页
Journal of Shenyang Medical College
关键词
脂蛋白相关磷脂酶A2
动脉粥样硬化
急性脑梗死
lipoprotein associated phospholipase A2
atherosclerosis
acute cerebral infarction