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基于聚类分析探讨余德钊教授治疗小儿腺样体肥大的用药规律 被引量:2

Medication rules of professor YU Dezhao in the treatment of children with adenoidal hypertrophy based on cluster analysis
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摘要 目的采用聚类分析的方法对余德钊教授治疗小儿腺样体肥大的中药处方的用药规律进行分析,归纳总结余教授治疗小儿腺样体肥大的用药经验。方法选取2018年4月至2019年4月广东省第二中医院儿科余德钊教授门诊就诊的60例腺样体肥大患儿的240首中药处方,采取Hierarchical Cluster分析的方法对处方中药味的频数和频率进行分析,总结余教授治疗小儿腺样体肥大的用药规律。结果有5味药出现频率>90%,9味药介于50%~89%,6味药为25%~49%,6味药<25%。余教授治疗小儿腺样体肥大最常用的是清热药,频率为36.44%;理气药次之,频率为18.40%;解表药位居第3,频率为14.85%。240首处方中主要针对风热壅肺型、痰热搏结型、气滞瘀热型、肺热阴虚型4种小儿腺样体肥大证型进行治疗,其中治疗痰热搏结型最多,频率为58.33%;风热壅肺型次之,为27.08%;气滞血瘀型和肺热阴虚型分别为15.42%和2.50%。结论余教授基于小儿肺脾不足的生理特点,提出小儿腺样体肥大多以痰热搏结型居多,治疗上以清热解毒、化痰散结为法,兼行气化瘀、益气养阴。 Objective To analyse medication rules of professor YU Dezhao’s Chinese materia medica(CMM)prescriptions in the treatment of children with adenoidal hypertrophy(AH)based on cluster analysis,and to generalize and summarize his medication experience in treating children with AD.Methods From April 2018 to April 2019,240 CMM prescriptions of 60 cases of children with AH consulted in outpatient service of professor YU Dezhao in pediatrics department of Guangdong Provincial The Second Hospital of TCM were chosen.The frequency number and frequency of CMM ingredients in the prescription were analyzed by Hierarchical Cluster analysis method,a nd the medication rule of professor YU in the treatment of AH in children was summarized.Results The frequency of 5 ingredients CMM was more than 90%,9 ingredients CMM were between 50%and 89%,6 ingredients CMM were between 25%and 49%,and 6 ingredients CMM were less than 25%.Heat-clearing drug was the most commonly used for professor YU’s treatment of AH in children,with the frequency of 36.44%;the second was regulating qi drug,with the frequency of 18.40%;the third was relieving exterior syndrome drug,with the frequency of 14.85%.The 240 prescriptions were mainly targeted for 4 types of AH in children to treat:wind-heat encumbering lung type,phlegm heat combating and binding type,qi stagnation and blood stasis type,and lung heat yin deficiency type.Among them,the treatment of phlegm heat combating and binding type was the most,with the frequency of 58.33%;wind heat encumbering lung type was the second,with the frequency of 27.08%;qi stagnation and blood stasis type and lung heat yin deficiency type were 15.42%and 2.50%,respectively.Conclusion Based on the physiological characteristics of lung and spleen in children,professor YU proposes that the majority of children with AH is phlegm heat and blood stasis type.His treatment of AH takes clearing away heat and detoxification as well as reducing phlegm and resolving masses as the methods,combined with promoting circulation of qi and
作者 莫琼珊 吕颖 MO Qiongshan;LYU Yin(Department of TCM,Shenzhen Maternal and Child Health Hospital,Shenzhen,Guangdong,518110,China;Department of Pediatrics,Guangdong Provincial The Second Hospital of TCM,Guangzhou,Guangdong,510030,China)
出处 《中医儿科杂志》 2020年第5期36-40,共5页 Journal of Pediatrics of Traditional Chinese Medicine
关键词 腺样体肥大 儿童 聚类分析 临床经验 余德钊 adenoidal hypertrophy(AH) children cluster analysis clinical experience YU Dezhao
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