摘要
目的:观察化瘀清肺汤联合西药治疗慢性阻塞性肺疾病的临床疗效及其对患者肺功能的影响。方法:将80例慢性阻塞性肺疾病患者按照随机数字表法分为对照组和观察组,每组各40例。对照组接受常规西药治疗,观察组在对照组的基础上加用化瘀清肺汤治疗。比较两组患者的临床疗效及治疗前后中医证候评分、肺功能指标[用力肺活量(forced vital capacity,FVC)、第1秒用力呼气容积占预计值百分比(forced expiratory volume in the first second as a percentage of predicted value,FEV1%)、第1秒用力呼气容积/用力肺活量(FEV1/FVC)]、血气分析指标[动脉血氧分压(arterial partial pressure of oxygen,PaO2)、动脉血二氧化碳分压(arterial partial pressure of carbon dioxide,PaCO2)]、血清T淋巴细胞(CD4^+、CD8^+)检测结果变化情况。结果:对照组有效率为80.00%,观察组有效率为95.00%,两组患者有效率比较,差异具有统计学意义(P<0.05)。两组患者治疗后中医证候评分低于本组治疗前,且观察组治疗后低于对照组治疗后,差异具有统计学意义(P<0.05)。两组患者治疗后FVC、FEV1%、FEV1/FVC、PaO2、CD4^+、CD4^+/CD8^+高于本组治疗前,PaCO2、CD8^+均低于同组治疗前,组内比较,差异具有统计学意义(P<0.05);观察组患者治疗后FVC、FEV1%、FEV1/FVC、PaO2、CD4^+、CD4^+/CD8^+均高于对照组,PaCO2、CD8^+低于对照组,组间比较,差异具有统计学意义(P<0.05)。结论:化瘀清肺汤联合西药治疗慢性阻塞性肺疾病,能够有效改善患者肺功能和免疫功能。
Objective:To observe the clinical curative effect of Decoction for Removing Blood Stasis and Clearing Lung in combination with Western medicine on chronic obstructive pulmonary disease(COPD) and its influence on lung function of patients.Methods:A total of 80 patients with COPD were randomly divided into the control group and the observation group according to random number table method,with 40 cases in each group.The control group received conventional Western medicine treatment,and the observation group received Decoction for Removing Blood Stasis and Clearing Lung on the basis of the control group.The clinical efficacy,the changes of TCM syndrome score,pulmonary function indexes [including forced vital capacity(FVC),forced expiratory volume in the first second as a percentage of predicted value(FEV1%),forced expiratory volume/forced vital capacity in the first second(FEV1/FVC)],blood-qi analysis indexes including arterial partial pressure of oxygen(PaO2),arterial partial pressure of carbon dioxide(PaCO2) and serum T lymphocyte(CD4^+、CD8^+)detection results were compared.Results:The effective rate of the control group was 80.00%,and that of the observation group was 95.00%.The difference was statistically significant(P<0.05).After the treatment,the TCM syndrome score of the two groups was lower than that of the same group before the treatment,and the TCM syndrome score of the observation group was lower than that of the control group after treatment,the difference was statistically significant(P<0.05).After the treatment,FVC,FEV1%,FEV1/FVC,PaO2,CD4^+ and CD4^+/CD8^+ in the two groups were higher than those of the same group before the treatment,while PaCO2 and CD8^+ were lower than those before the treatment in the same group,and all the differences were statistically significant in the same group(P<0.05).After the treatment,FVC,FEV1%,FEV1/FVC,PaO2,CD4^+ and CD4^+/CD8^+ in the observation group were higher than those of the control group,while its PaCO2 and CD8^+ were lower than those in the control group,and
作者
杨照明
YANG Zhao-ming(Puyang Fifth People′s Hospital,Puyang,Henan,China,457000)
出处
《河南中医》
2020年第10期1552-1555,共4页
Henan Traditional Chinese Medicine
基金
河南省中医药科学研究专项课题项目(2015ZY02037)。
关键词
慢性阻塞性肺疾病
化瘀清肺汤
肺功能
免疫功能
chronic obstructive pulmonary disease(COPD)
Decoction for Removing Blood Stasis and Clearing Lung
lung function
immune function
