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西酞普兰结合米氮平对抑郁症患者睡眠质量与抑郁情绪的影响 被引量:2

Citalopram Combined with Mirtazapine on Sleep Quality and Effects of Depression
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摘要 目的探讨西酞普兰结合米氮平对抑郁症患者睡眠质量与抑郁情绪的影响。方法选取2017年8月-2018年8月80例抑郁症患者,随机分组,对照组40例,单用西酞普兰治疗,观察组40例,用西酞普兰联合米氮平治疗。比较两组治疗前后抑郁评分(SDS)及治疗前后睡眠质量评分。结果治疗前,两组抑郁评分差别不明显(P>0.05),治疗后,观察组SDS评分比对照组低(P<0.05);治疗前,两组睡眠质量评分差异不明显(P>0.05),治疗后,观察组睡眠质量评分比对照组高(P<0.05)。结论对抑郁症患者用米氮平与西酞普兰联合治疗,患者抑郁情绪缓解,睡眠质量改善。 Objective To explore the effect of citalopram combined with mirtazapine on sleep quality and depression in patients with depression.Methods Eighty patients with depression in our hospital were selected.Treatment period:August 2017-August 2018.Randomly divided into 40 cases in the control group,treated with citalopram alone,and 40 cases in the observation group.Niazapine treatment.The depression score(SDS)before and after treatment and the sleep quality score before and after treatment were compared between the two groups.Results Before treatment,there was no significant difference in depression scores between the two groups(P>0.05).After treatment,the SDS score of the observation group was lower than that of the control group(P<0.05);before treatment,there was no significant difference in sleep quality score between the two groups(P>0.05),After treatment,the sleep quality score of the observation group was higher than that of the control group(P<0.05).Conclusions The combination of mirtazapine and citalopram is used to treat patients with depression.The patient′s depression is relieved and sleep quality is improved.This method can be clinically popularized.
作者 金玲 马学森 JIN Ling;MA Xues-en(China Guihang Group 302 Hospital Anshun,Guizhou 561000)
机构地区 中国贵航集团
出处 《航空航天医学杂志》 2020年第8期915-916,共2页 Journal of Aerospace medicine
关键词 抑郁症 西酞普兰 米氮平 睡眠质量 抑郁评分 depression citalopram mirtazapine sleep quality depression score
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