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罗布麻抑菌物质及其作用机制的研究进展 被引量:8

Research progress in antibacterial substances from Apocynum venetum and their antibacterial mechanism
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摘要 为阐明罗布麻抑菌功能的物质基础,促进罗布麻纤维在医疗保健用纺织品领域的开发和应用,综述了罗布麻韧皮和精干麻纤维中存在的主要抑菌物质,包括:黄酮类化合物、鞣质、甾体及其苷类、香豆素类化合物、酚酸类和苯甲醛类化合物、脂肪酸以及挥发油。分析了各类抑菌物质的化学成分和抑菌活性,并着重从抑制核酸合成、破坏细胞膜、抑制能量代谢、影响脂肪酸合成、抑制运动性、阻断电子传递链、抑制酶活性、减弱营养物质的吸收以及通过过氧化和自氧化形成具有毒性的降解产物等方面介绍了抑菌作用机制。最后针对精干麻纤维抑菌物质的来源问题,指出韧皮中功能性成分在脱胶过程中的演化行为应成为未来研究的一个重要方向。 In order to elucidate the material basis for antibacterial property of Apocynum venetum(A.venetum)and facilitate the development and application of A.venetum fiber in medical and healthcare textiles,antibacterial substances in the bast of A.venetum and its technical fiber were reviewed and summarized including flavonoids,tannins,steroids,steroid glycosides,coumarins,phenolic acids,benzaldehydes,fatty acids and essential oils.The chemical composition and antibacterial activity of antibacterial substances were analyzed.Antibacterial mechanisms including inhibition of nucleic acid synthesis,membrane damage of the cell,inhibition of energy metabolism,effect on fatty acid synthesis,inhibition of migration,disrupting electron transport chain,inhibition of activity of bacterial enzymes,reduction in the absorption of nutrients and generation of toxic peroxidation and auto-oxidation degradation products were also highlighted.Finally,focusing on the problem of the origin of antibacterial substances of A.venetum fiber,it was pointed out that evolution of functional ingredients in the bast during degumming process should become an important direction for future study.
作者 徐绚绚 巩继贤 张健飞 王莉 黄景凤 XU Xuanxuan;GONG Jixian;ZHANG Jianfei;WANG Li;HUANG Jingfeng(School of Textile Science and Engineering, Tiangong University, Tianjin 300387, China;Key Laboratory of Advanced Textile Composites, Ministry of Education, Tiangong University, Tianjin 300387, China;Collaborative Innovation Center for Eco-Textiles of Shandong Province, Qingdao, Shandong 266071, China;Altay Gaubau Tea Co., Ltd., Altay, Xinjiang 836500, China)
出处 《纺织学报》 EI CAS CSCD 北大核心 2020年第9期149-154,共6页 Journal of Textile Research
基金 国家重点研发计划项目(2016YFC0400503-02) 中国纺织工业联合会科技指导性项目(2017011) 天津市自然科学基金项目(18JCYBJC89600) 新疆维吾尔自治区重大专项资助项目(2016A03006-3)。
关键词 罗布麻 韧皮 抑菌物质 抑菌活性 抑菌机制 Apocynum venetum bast antibacterial substances antibacterial activity antibacterial mechanism
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