摘要
目的探究急性重症胰腺炎患者应用早期肠内营养的治疗效果及对氨基酸代谢的影响。方法选取2018年4月至2019年6月本院收治的急性重症胰腺炎患者50例,将所选患者随机分为研究组与对照组,每组25例。对照组女13例,男12例,年龄(49.6±0.2)岁,运用常规的治疗方式及肠外营养治疗;研究组女11例,男14例,年龄(50.1±0.6)岁,运用肠内营养治疗的方式。比较两组并发症、血尿素、肝糖原含量、血糖和治疗效果。结果研究组发生肺炎、腹腔脓肿、胰腺感染、胰腺坏死等并发症例数分别为2例、1例、1例和0例,明显少于对照组的5例、7例、4例、9例(均P<0.05);研究组干预后血尿素、肝糖原含量以及血糖浓度明显高于对照组[(5.4±1.2)mmol/L比(4.2±0.3)mmol/L、(49.7±0.4)比(43.2±1.3)、(261.3±1.2)比(248.1±2.1),均P<0.05];研究组治疗1月后治疗有效率明显高于对照组(96.0%比64.0%,P<0.05)。结论相对于常规的治疗方式,肠内营养治疗的方式具有见效快、安全性高以及并发症低的优势,能够提高患者在治疗期间的生活质量,在重症急性胰腺炎治疗的应用效果理想,临床上应当进一步推广应用。
Objective To investigate the therapeutic effect of early enteral nutrition for acute severe pancreatitis and its effect on amino acid metabolism.Methods 50 patients with severe acute severe pancreatitis treated at our hospital from April,2018 to June,2019 were selected,and were randomly divided into a research group and a control group,with 25 cases in each group.The control group,including 13 female and 12 male cases who were(49.6±0.2)years old,took conventional treatment and parenteral nutrition.The research group,including 11 female and 14 male who were(50.1±0.6)years old,took enteral nutrition.The complications,urea,liver glycogen,blood glucose,and treatment effect were compared between these two groups.Results 2,1,1,and 0 in the research group and 5,7,4,and 9 in the control group had pneumonia,abdominal abscess,pancreatic infection,and pancreatic necrosis,respectively,with statistical differences(all P<0.05).The levels of blood urea,liver glycogen,and blood glucose were higher in the research group than in the control group[(5.4±1.2)mmol/L vs.(4.2±0.3)mmol/L,(49.7±0.4)vs.(43.2±1.3),and(261.3±1.2)vs.(248.1±2.1);all P<0.05].After 1 month’s treatment,the treatment effective rate was significantly higher in the research group than in the control group(96.0%vs.64.0%;P<0.05).Conclusion Compared with the conventional treatment,enteral nutrition has the advantages of quick response,high safety,and a low incidence of complications,and can improve the patients’quality of life.It has an ideal effect in the treatment of severe acute pancreatitis,and should be further popularized in clinical practice.
作者
周东华
Zhou Donghua(Second People’s Hospital of Lijin County,Dongying 257447,China)
出处
《国际医药卫生导报》
2020年第18期2791-2793,共3页
International Medicine and Health Guidance News
关键词
急性重症胰腺炎
早期肠内营养治疗
氨基酸代谢
Acute severe pancreatitis
Early enteral nutrition therapy
Amino acid metabolism
