摘要
目的探讨地屈孕酮联合黄体酮对高龄二胎先兆流产保胎成功率及β-HCG、孕激素和雌激素水平的影响。方法选取2013年1月至2018年12月西安高新医院诊治的120例高龄第二胎次先兆流产孕妇作为研究对象。随机分为试验组(n=60)和对照组(n=60),试验组孕妇给予地屈孕酮联合黄体酮和常规对症治疗,对照组孕妇仅给予黄体酮和常规对症治疗,观察两组孕妇治疗后的保胎成功率,β-HCG和孕激素及雌激素水平。结果试验组孕妇治疗后保胎成功率高于对照组孕妇,治疗后血清β-HCG、孕激素和雌激素水平大于对照组孕妇,差异均具有统计学意义(均P<0.05)。结论地屈孕酮联合黄体酮对高龄第二胎次先兆流产具有较高的保胎成功率,可有效改善血清β-HCG、孕激素及雌激素水平。
Objective To investigate the effects of dydrogesterone combined with progesterone on the success rate of threatened abortion,the level ofβ-human chorionic gonadotropin(HCG),progesterone and estrogen in elderly pregnant women giving second birth.Methods 120 pregnant women giving second birth with threatened abortion were collected in Xi′an High-tech Hospital from January 2013 to December 2018 and randomly divided into experimental group and control group,60 cases in each group.The experimental group was given dydrogesterone combined with progesterone and routine symptomatic treatment,while the control group was given progesterone and routine symptomatic treatment only.The success rate,levels ofβ-HCG,progesterone and estrogen were recorded and compared between the two groups.Results After treatment,the success rate of fetal protection in the experimental group was higher than that in the control group,and the levels of serumβ-HCG,progesterone and estrogen in the experimental group were higher than those in the control group,all with statistically significant differences(all P<0.05).Conclusions Dydrogesterone combined with progesterone has a higher success rate for threatened abortion in elderly pregnant women giving second birth,and can effectively improve serum levels ofβ-HCG,progesterone and estrogen.
作者
黎兴利
孙燕
LI Xingli;SUN Yan(Department of Obstetrics,Xi'an High-tech Hospital,Xi'an 710065,Shaanxi,China)
出处
《中国性科学》
2020年第8期42-44,共3页
Chinese Journal of Human Sexuality
关键词
地屈孕酮
黄体酮
先兆流产
保胎成功率
HCG
孕激素
雌激素
Dydrogesterone
Progesterone
Threatened abortion
Prenatal success rate
Human chorionic gonadotropin(HCG)
Estrogen
