摘要
目的明确骨质疏松女性股骨颈骨折与股骨转子间骨折的髋部骨密度差异,探讨骨质疏松患者发生髋部骨折(股骨颈骨折、股骨转子间骨折)与骨折部位骨密度的相关性。方法回顾性分析2015年1月1日至2016年12月31日期间于福建省某三级甲等医院的住院治疗的骨质疏松及髋部骨质疏松性骨折患者172例,其中无病史的原发骨质疏松患者109例、骨质疏松性股骨颈骨折患者39例、骨质疏松性转子间骨折24例。分别统计3组患者年龄、体质指数、糖尿病患病情况、骨折侧别、髋部各部位骨密度、血清I型胶原交联C末端肽(C-terminal crosslinking telopeptide of type I collagen,CTX)、I型原胶原N-端前肽(procollagen type I N propeptide,PINP)、25羟基维生素D(25-OH-D)。分别进行三组间及两两组间比较。结果三组间年龄、体质指数、糖尿病患病率差异无统计学意义(F=2.667,P=0.072;F=0.882,P=0.416;χ^2=3.216,P=0.232),股骨颈骨折组与股骨转子间骨折组组间骨折侧别差异无统计学意义(χ^2=0.958,P=0.328),三组间髋部Ward区骨密度差异无统计学意义(F=2.937,P=0.056),髋部骨密度比较,股骨颈、股骨大转子、股骨转子间、髋部整体差异有统计学意义(F=7.825,P=0.001;F=8.668,P<0.001;F=9.657,P<0.001)。股骨颈骨折组、转子间骨折组股骨颈、股骨大转子、股骨转子间、髋部整体骨密度均小于骨质疏松组,差异均有统计学意义(P<0.05);股骨颈骨折组与转子间骨折组股骨颈、大转子、转子间、髋部整体骨密度差异均无统计学意义(P>0.05)。三组间β-CTX、P1NP、维生素D差异均有统计学意义(P<0.05)。股骨颈骨折组、转子间骨折组β-CTX、维生素D均小于骨质疏松组,差异均有统计学意义(P<0.05);转子间骨折与骨质疏松组P1NP差异无统计学意义,股骨颈骨折组与转子间骨折组股骨颈、大转子、转子间、髋部整体骨密度差异均无统计学意义(P>0.05)。结论女性骨质�
Objective To determine the difference of hip bone mineral density between femoral neck fracture and intertrochanteric fracture in women with osteoporosis,and to explore the correlation between hip fracture(femoral neck fracture,intertrochanteric fracture)and bone mineral density at the fracture site in patients with osteoporosis.Methods A retrospective analysis of 172 patients with osteoporosis and hip osteoporotic fractures who were hospitalized in a tertiary A hospital in Fujian Province from January 1,2015 to December 31,2016,including 109 cases of patients with a history of primary osteoporosis,39 patients with osteoporotic femoral neck fracture,24 cases of osteoporotic fracture between the rotor.The age,body mass index,prevalence of diabetes,fracture side,bone density of each hip area,C-terminal crosslinking telopeptide of type I collagen,procollagen type I N propeptide,25-OH-VitD were calculated respectively.Comparisons were made among three groups and two groups.Results There were no significant differences in age,body mass index,and diabetes prevalence among the three groups(F=2.667,P=0.072;F=0.882,P=0.416;χ^2=3.216,P=0.232).There was no statistically significant difference in hip ward area density difference between the femoral neck fracture group and the femoral intertrochanteric fracture group(χ^2=0.958,P=0.328),and there was no statistically significant difference in the bone mineral density of the hip ward area among the three groups(F=2.937,P=0.056).The comparison of hip bone mineral density,femoral neck,femoral greater trochanter,between the femur rotor,hip overall were statistically significant(F=7.825,P<0.05,P=0.001;F=8.668,P<0.001;F=9.657,P<0.001).The overall BMD of femoral neck,greater trochanter,intertrochanteric and hip in the femoral neck fracture group and the intertrochanteric fracture group were all lower than those in the osteoporosis group,and the difference was statistically significant(P<0.05).The overall BMD of femoral neck,greater trochanter,intertrochanter and hip in the femoral
作者
吴少明
谢俊杰
刘夏莹
卢天祥
吴世强
吴文华
WU Shaoming;XIE Junjie;LIU Xiaying;LU Tianxiang;WU Shiqiang;WU Wenhua(Department of Orthopedics, Quanzhou First Hospital Affiliated to Fujian Medical University, Quanzhou 362000, China;Prenatal Diagnosis Center of Quanzhou Maternal and Child Health Hospital and Children’s Hospital, Quanzhou 362000, China;Department of Orthopedics, The Second Affiliated Hospital of Fujian Medical University, Quanzhou 362000, China)
出处
《中国骨质疏松杂志》
CAS
CSCD
北大核心
2020年第10期1500-1504,共5页
Chinese Journal of Osteoporosis
关键词
骨质疏松性骨折
股骨颈骨折
股骨转子间骨折
骨密度
osteoporotic fracture
fracture of femoral neck
intertrochanteric fracture
bone mineral density
