摘要
交感性眼炎(SO)是指单眼外伤或进行内眼手术后发生的双眼非坏死性肉芽肿性葡萄膜炎。其发病机制尚未明确,多认为是自身抗原暴露导致的免疫性疾病。临床诊断主要依靠患者病史、典型的临床表现和体征以及FFA、ICGA、OCT等眼科影像学辅助检查。SO临床表现复杂多样,病情易于反复,最终可能致盲。目前主要通过系统性糖皮质激素治疗联合免疫抑制剂和(或)生物制剂等药物进行治疗。了解SO的典型影像学表现,有助于临床上早期明确诊断,及时给予合理的药物治疗,改善患者预后。
Sympathetic ophthalmia(SO)is a bilateral granulomatous uveitis that occurs after single eye surgery or internal eye surgery.Its pathogenesis is not yet clear,and it is mostly considered to be an immune disease caused by exposure to autoantigens.The clinical diagnosis mainly depends on the patient's medical history,typical clinical manifestations and signs,and auxiliary ophthalmic imaging examinations such as FFA,ICGA,OCT.The clinical manifestations of SO are complex and variable,and the disease is prone to relapse,which may eventually lead to blindness.At present,treatment is mainly through systemic glucocorticoid therapy combined with immunosuppressive agents and/or biological agents.Understanding the typical imaging manifestations of SO is helpful to confirm the diagnosis early in the clinic,and timely provide reasonable drug treatment to improve the prognosis of patients.
作者
李伊茗
颜华
Li Yiming;Yan Hua(Department of Ophthalmology,Tianjin Medical University General Hospital,Tianjin 300052,China)
出处
《中华眼底病杂志》
CAS
CSCD
北大核心
2020年第9期730-734,共5页
Chinese Journal of Ocular Fundus Diseases
基金
国家自然科学基金(重点项目)(81830026)
国家自然科学基金(面上项目)(31871184)
国家杰出青年科学基金(81800815)
天津市重大疾病防治科技重大专项(18ZXDBSY00030)。
关键词
眼炎
交感性/诊断
眼炎
交感性/治疗
综述
Ophthalmia,sympathetic/diagnosis
Ophthalmia,sympathetic/therapy
Review
