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113例登革热患者的中医证治分析 被引量:1

Syndrome Differentiation and Treatment of Dengue Fever:An Analysis of 113 Cases
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摘要 【目的】基于六经辨证理论分析登革热患者的中医证治特点。【方法】回顾性分析广东省中医院芳村医院2019年7~10月所收治的113例登革热患者的临床病例资料,按照是否使用经方中药汤剂治疗,分为中药组76例和西药常规组37例。总结所纳入病例的中医证候分布及六经辨证的中医证型分布特点,比较2组患者退热时间、白细胞计数(WBC)及血小板计数(PLT)的差异及升白药物使用情况。【结果】(1)中医证候分布方面:在纳入的113例登革热患者中,以发热、头痛为主要临床表现(分别占96.46%和95.58%),同时88.50%的患者伴有周身疼痛,且以肩背部与双髋部为甚;61.95%的患者出现皮疹,且以红色针尖样丘疹多见,并多伴有瘙痒;此外,约有40%~80%的患者伴有纳差/纳呆、腹泻、恶心呕吐等胃肠功能紊乱的症状。(2)六经辨证方面:113例登革热患者的中医证型分布频次由多到少分别为少阳阳明证、少阳证、太阳阳明证、阳明证、太阴证、太阳证。(3)退热时间方面:中药组的退热时间明显短于西药常规组,差异有统计学意义(P<0.05)。(4)实验室指标方面:治疗3 d后,2组患者WBC水平均较治疗前升高(P<0.05),而2组PLT水平均无明显变化(P>0.05);组间比较,2组患者的WBC和PLT水平均无统计学差异(P>0.05)。【结论】基于六经辨证,登革热患者的中医证型以少阳阳明证、少阳证、太阳阳明证为多,使用经方治疗可有助于改善患者证候,缩短患者退热时间。 Objective To analyze the clinical characteristics of dengue fever treated with Chinese medicine based on the syndrome differentiation of six meridians. Methods A retrospective study was carried out in 113 cases of dengue fever admitted in Fangcun Branch Hospital of Guangdong Provincial Hospital of Traditional Chinese Medicine from July to October of 2019. According to the medication of classical Chinese medicine prescriptions or not,the patients were divided into Chinese medicine group(76 cases)and control group(37 cases,treated with conventional western medicine). The clinical data of the 113 cases of dengue fever were collected for the retrospective analysis of the distribution of the traditional Chinese medicine(TCM)syndromes and the six-meridian syndrome types. And the antipyretic time,white blood cell(WBC)count and platelet(PLT)count as well as the medication of leukocytopoiesis-promoting drugs between the two groups were compared. Results(1)Among the113 included cases of dengue fever,fever and headache were the main clinical manifestations,which accounted for 96.46%,95.58% respectively. And 88.50% of the patients were accompanied by the pain all over the body,especially in shoulder,back and hips. Skin rash occurred in 61.95% of the patients,mainly characterized by red pointed papule and accompanied by pruritus. Moreover,about 40% ~ 80% of the patients had the gastrointestinal function disorders such as poor appetite or anorexia,diarrhea,nausea and vomiting.(2)In respect of the sixmeridian syndrome types,113 dengue fever patients had the Shaoyang Yangming syndrome,Shaoyang syndrome respectively, Taiyang Yangming syndrome, Yangming syndrome, Taiyin syndrome and Taiyang syndrome respectively,and their percentages were in decreasing sequence.(3)The antipyretic time of Chinese medicine group was significantly shorter than that of the control group,and the difference was statistically significant(P<0.05).(4)In respect of the laboratory indicators, WBC count in the two groups after 3 days of treatment was increase
作者 汤宛莹 王进忠 郭权来 俞骄丽 高业勤 覃小兰 TANG Wan-Ying;WANG Jin-Zhong;GUO Quan-Lai;YU Jiao-Li;GAO Ye-Qin;QIN Xiao-Lan(The Second Clinical Medical School of Guangzhou University of Chinese Medicine,Guangzhou 510405 Guangdong,China;The Second Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510120 Guangdong,China)
出处 《广州中医药大学学报》 CAS 2020年第10期1845-1849,共5页 Journal of Guangzhou University of Traditional Chinese Medicine
基金 广东省中医急症研究重点实验室建设项目(编号:2017B030314176) 广东省中医院岭南岑氏杂病流派传承工作室(编号:E43602)。
关键词 登革热 中医证候分布 六经辨证 经方 dengue fever distribution of traditional Chinese medicine syndromes six-meridian syndrome differentiation classic Chinese medicine prescriptions
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