摘要
目的对广州市新型冠状病毒肺炎(COVID-19)疫情的流行特征进行分析,为指导疫情防控提供科学依据。方法对广州市COVID-19确诊病例及无症状感染者进行流行病学调查,采用描述流行病学方法描述流行特征及病例临床特征,分析感染来源及与疾病严重程度相关因素。结果截至2020年3月11日,广州市共报告361例新型冠状病毒感染者,其中确诊病例347例(占96.1%),无症状感染者14例。病例以外地输入为主,占73.2%,其中80.3%为湖北省输入(204/254)。63.7%的病例与聚集性疫情关联,且以家庭聚集为主(占85.1%)。最常见症状为发热(占78.1%),其次为干咳(占45.9%)。93.9%的病例表现为轻型或普通型,仅1例死亡。男性、高龄、职业为离退人员、自述有心脑血管疾病史和发病前14 d内有医疗机构就诊史等因素与重症型病例有关(P<0.05或P<0.01)。结论广州市COVID-19疫情以湖北省输入为主,部分地区出现本地感染,家庭聚集性疫情多发,但尚未发生社区传播,提示在以输入病例为主的地区采取加强主动排查、严格隔离确诊病例和密切接触者等措施,可有效控制本地传播。
Objective To analyze characteristics of coronavirus disease 2019(COVID-19)epidemic in Guangzhou,so as to provide scientific evidence for prevention and control practice.Methods Epidemiological investigation was carried out on the confirmed COVID-19 patients and asymptomatic cases in Guangzhou.The epidemiological and clinical characteristics of the cases were described by descriptive epidemiological method,and factors related to the source of infection and disease severity were determined.Results As of March 11,2020,a total of 361 COVID-19 cases were reported in Guangzhou,including 347 confirmed cases(96.1%)and 14 cases of asymptomatic infection.The cases were mainly imported from areas outside Guangzhou(73.2%)and 80.3%of them were imported from Hubei Province(204/254).Of the confirmed cases,63.7%were associated with cluster outbreaks,of which 85.1%were household clusters;93.9%developed mild symptoms or common pneumonia.The most common symptom was fever(78.1%),followed by dry cough(45.9%).Only one death was reported.Factors including male,elder age-group,retirees,self-reported having a history of cardiovascular disease or having a history of admission to medical institutions 14 days prior to disease onset were associated with serious cases(P<0.05 or P<0.01).Conclusion The COVID-19 cases in Guangzhou were mainly imported from Hubei Province,local infections occurred in some areas,and many were household clusters,but no community transmission was observed.
作者
马蒙蒙
马晓薇
吴燕
李琴
步犁
梁颖茹
张玉华
甄若楠
李科
陈雄飞
张维蔚
董志强
景钦隆
罗雷
MA Meng-meng;MA Xiao-wei;WU Yan;LI Qin;BU Li;LIANG Ying-ru;ZHANG Yu-hua;ZHEN Ruo-nan;LI Ke;CHEN Xiong-fei;ZHANG Wei-wei;DONG Zhi-qiang;JING Qin-long;LUO Lei(Guangzhou Center for Prevention and Control,Guangzhou 510440,China)
出处
《华南预防医学》
2020年第4期380-384,共5页
South China Journal of Preventive Medicine
基金
广州市卫生健康科技项目(20191A011058)
广州市科技计划项目(201904010154)。
关键词
新型冠状病毒肺炎
新发传染病
流行病学
COVID-19
Epidemiological characteristics
Emerging infectious disease
