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液体活检在胰腺癌诊治中的应用价值 被引量:2

Application value of liquid biopsy in diagnosis and treatments of pancreatic cancer
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摘要 胰腺癌是一种恶性程度高、预后差的消化系统恶性肿瘤,由于缺乏有效的早期诊断方法,超过80%的胰腺癌患者在确诊时已处于中晚期,故手术切除率低、术后复发率高[1]。近年来随着肿瘤基因组学的深入研究和高通量测序技术的发展,以循环肿瘤细胞(circulating tumor cells,CTC)、循环肿瘤DNA(circulating tumor DNA,ctDNA)、外泌体等为代表的液体活检技术为胰腺癌的精准诊治带来了新的曙光[2-4]。
作者 杨正江 辛万鹏 肖卫东 Yang Zhengjiang;Xin Wanpeng;Xiao Weidong
出处 《中华肝脏外科手术学电子杂志》 CAS 2020年第5期425-428,共4页 Chinese Journal of Hepatic Surgery(Electronic Edition)
基金 国家自然科学基金(81660401,81860418) 江西省重点研发计划一般项目(20192BBG70035)。
关键词 胰腺肿瘤 活组织检查 肿瘤细胞 循环 外泌体 Pancreatic neoplasms Biopsy Neoplastic cells circulating Exosomes
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