摘要
目的分析间断爆发模式脉冲刺激(iTBS)经颅磁刺激治疗缺血性脑卒中后吞咽障碍的临床价值。方法选取海南医学院第二附属医院2018年1月-2019年12月收治的60例恢复期缺血性脑卒中后吞咽障碍患者,采用随机数字表双盲法分为治疗组与对照组,各30例。两组均给予常规吞咽康复治疗,在此基础上,治疗组给予iTBS经颅磁刺激,对照组给予假低频重复经颅磁刺激,两组均治疗2周。统计对比两组临床疗效、治疗前后吞咽功能(SSA评分)、洼田饮水试验等级评分、摄食功能(FOIS评分)及生活质量(SWAL-QOL评分)改善情况以及治疗安全性。结果治疗组总有效率(90.0%)高于对照组(66.67%),差异有统计学意义(P<0.05);治疗1周、2周后,两组SSA评分均较治疗前降低,且治疗组较对照组明显降低,差异有统计学意义(P<0.05);治疗1周、2周后,两组洼田饮水试验等级评分较治疗前降低,且治疗组较对照组明显降低,差异有统计学意义(P<0.05);治疗1周、2周后,两组FOIS评分较治疗前增加,且治疗组较对照组明显增加,差异有统计学意义(P<0.05);治疗1周、2周后,两组SWAL-QOL评分较治疗前增加,且治疗组较对照组明显增加,差异有统计学意义(P<0.05);治疗期间,两组均未见头痛、疲乏、焦虑、耳鸣等不良事件发生。结论缺血性脑卒中后吞咽障碍采取iTBS经颅磁刺激效果显著,可恢复患者吞咽功能,提升生活质量,且具有安全性。
Objective To analyze the clinical value of transcranial magnetic stimulation with iTBS in treatment of dysphagia after ischemic stroke.Methods A total of 60 patients with dysphagia after ischemic stroke were randomly divided into treatment group and control group with 30 cases in each group.Both groups were treated with routine swallowing rehabilitation,based on which the treatment group was given iTBS transcranial magnetic stimulation,while the control group was given false low-frequency repetitive transcranial magnetic stimulation for 2 weeks.The clinical effect,improvement of swallowing function(SSA score)and quality of life(swal-qol score)before and after the treatments,and treatment safety were statistically compared between the two groups.Results The total clinical effective rate was 90.0%in the treatment group and 66.67%in the control group,the difference was statistically significant(P<0.05).After 1 and 2 weeks of the treatment,the SSA scores and grade scores of the two groups were lower than those before the treatment(P<0.05);the Fois scores and swal-qol scores of the two groups were higher than those before the treatment(P<0.05).During the treatment,no adverse events such as headache,fatigue,anxiety and tinnitus were found in the two groups.Conclusion iTBS transcranial magnetic stimulation can restore the swallowing function,improve the quality of life and have safety.
作者
吴秀香
李晓丹
王莉
符翔成
蒋惠瑜
WU Xiuxiang;LI Xiaodan;WANG Li;FU Xiangcheng;JIANG Huiyu(Department of Rehabilitation Medicine,the Second Affiliated Hospital of Hainan Medical College,Haikou 570311,China;Department of Otorhinolaryngology Head and Neck Surgery,the Second Affiliated Hospital of Hainan Medical College,Haikou 570311,China)
出处
《新疆医科大学学报》
CAS
2020年第9期1228-1232,共5页
Journal of Xinjiang Medical University
基金
海南省医药卫生科研项目(1801320141A2001)。
关键词
缺血性脑卒中
吞咽障碍
iTBS经颅磁刺激
吞咽功能
生活质量
ischemic stroke
dysphagia
transcranial magnetic stimulation of iTBS
swallowing function
quality of life
