摘要
局灶性白质损伤(punctate white matter lesions,PWML)是婴儿期最为常见的白质损伤性疾病(发生率超过20%),可引起不良神经发育结局,严重威胁患儿的身心健康发展。该损伤具有多变性及扩展性,可导致广泛脑结构及功能变化。笔者主要阐述了PWML病灶特征及其预后评估方面的研究进展,指出现有损伤评估中存在的问题并进行展望。
Punctate white matter lesions(PWML)are prevalent white matter disease in infant(more than 20%),and may result in adverse neurodevelopmental outcomes.The injury has the characteristics of variability and expansibility,which can lead to extended alterations in brain structures and function.This paper mainly introduces the research progress of lesion characteristics and prognosis of PWML,and point out the existing problems and prospects in evaluation of PWML.
作者
王苗苗
刘聪聪
杨健
WANG Miaomiao;LIU Congcong;YANG Jian(Department of Radiology,the First Affiliated Hospital of Xi’an Jiaotong University,Xi’an 710061,China)
出处
《磁共振成像》
CAS
2020年第8期699-703,共5页
Chinese Journal of Magnetic Resonance Imaging
基金
国家自然科学基金(编号:81771810,81971581)
国家重点研发计划(编号:2016YFC0100300)。
关键词
局灶性白质损伤
脑结构
脑功能
磁共振成像
预后评估
婴儿
punctate white matter lesions
brain structure
brain function
magnetic resonance imaging
outcome assessment
infant
