摘要
报道2例角层下脓疱性皮病,皮损均表现为红斑基础上的水疱、脓疱,组织病理学特征为角层下脓疱,直接免疫荧光阴性;脓疱疱液细菌培养阴性。患者1,女,53岁,合并类风湿关节炎。口服阿维A,糖皮质激素和羟氯喹治疗。患者2,女,69岁,合并干燥综合症及自身免疫性肝炎,予糖皮质激素及米诺环素治疗。2例患者均好转。
Two cases of subcorneal pustular dermatosis were reported.The two patients presented with erythemas and pustules over the trunk.Histopathology showed subcorneal pustules.DIF was negative and there was no bacterial growth in pustules bacterial culture.Case 1 was a 53-year-old female with rheumatoid arthritis,and was treated with oral acitretin capsules,glucocorticoids and hydroxychloroquine.Case 2 was a 69-year-old female with Sjogren’s syndrome and autoimmune hepatitis,and was treated with glucocorticoids and minocycline.The lesions of both patients subside.
作者
刘洋爱
董正邦
王飞
LIU Yang’ai;DONG Zhengbang;WANG Fei(Department of Dermatology,Zhongda Hospital,Southeast University,Nanjing 210009,China)
出处
《中国麻风皮肤病杂志》
2020年第10期613-615,635,共4页
China Journal of Leprosy and Skin Diseases
关键词
角层下脓疱性皮病
结缔组织病
subcorneal pustular dermatosis
connective tissue disease
