摘要
目的探究肺癌与肺癌合并肺部感染患者血常规指标、血清炎性因子差异性。方法选取我院2017年11月~2019年11月进行诊断治疗的肺癌与肺癌合并肺部感染患者各36例,按照不同疾病情况分为观察组及对照组。单纯肺癌患者为对照组,肺癌合并肺部感染患者为观察组。对比两组血清炎性因子的水平、血常规指标及凝血指标情况,对比分析检测的结果。结果观察组患者的PLT、APTT、PT、TT、FIB、D-dimer凝血指标水平均高于对照组,差异有统计学意义(P<0.05);观察组患者的的LYM水平低于对照组,WBC、MONO及NEU血常规指标水平均高于对照组,差异有统计学意义(P<0.05);观察组患者的IL-6、TNF-α、IL-1β血清炎性因子水平指标均高于对照组,差异有统计学意义(P<0.05)。结论针对肺癌与肺癌合并肺部感染患者,血清炎性因子、凝血指标、血常规指标均存在较大差异,相较于对照组,观察组的凝血功能紊乱、肺部的炎症反应症状更严重,具有临床应用价值。
Objective To investigate the differences of blood routine indicators and serum inflammatory factors between patients with lung cancer and lung cancer complicated with lung infection.Methods 36 patients with lung cancer and 36 patiants with lung cancer complicated with lung infection who were diagnosed and treated in our hospital from November 2017 to November 2019 were selected and divided into the observation group and the control group according to different disease conditions.Patients with lung cancer alone were classified as the control group,and patients with lung cancer complicated with lung infection were classified as the observation group.The levels of serum inflammatory factors,blood routine indicators and blood coagulation indicators were compared and analyzed between the two groups.Results The levels of PLT,APTT,PT,TT,FIB and D-dimer coagulation indicators of the observation group were higher than those of the control group,with statistically significant differences(P<0.05).The LYM level of the observation group was lower than that of the control group,and the blood routine indicators of WBC,MONO and NEU were higher than those of the control group,with statistically significant differences(P<0.05)The levels of IL-6,TNF-α,IL-1βserum inflammatory factor of the observation group were higher than those of the control group,with statistically significant differences(P<0.05).Conclusion There are significant differences in serum inflammatory factors,blood coagulation indicators and blood routine indicators between patients with lung cancer and lung cancer complicated with lung infection.Compared with the control group,the coagulation function disorder and inflammation symptoms of the lung in the observation group are more serious,which has clinical application value.
作者
李华
蒙建凤
唐丽娟
LI Hua;MENG Jianfeng;TANG Lijuan(Department of Respiratory and Critical Care Medicine,Nanxishan Hospital of Guangxi Zhuang Autonomous Region,Guilin541002,China;Emergency Department,Affiliated Hospital of Guilin Medical University,Guilin541002,China)
出处
《中国现代医生》
2020年第24期113-115,共3页
China Modern Doctor
关键词
肺癌
肺部感染
血清炎性因子
血常规
Lung cancer
Lung infection
Serum inflammatory factors
Blood routine
