摘要
目的了解环磷腺苷在用药过程中可能出现的不良反应及原因。方法报道1例冠心病患者静脉滴注环磷腺苷后出现皮肤发痒、头晕胸闷、意识丧失,并通过查阅文献分析其可能原因。结果本次不良反应很可能由环磷腺苷引起,原因可能与患者本身疾病、配伍以及辅料有关。结论环磷腺苷临床使用广,安全性高,但也会造成严重的过敏性休克,临床应用时需谨慎。
OBJECTIVE To investigate the possible adverse reactions and course of adenosine cyclophosphate.METHODS Reported a case of coronary heart disease appearing itchy skin,dizziness,chest tightness and loss of consciousness after intravenous infusion of adenosine cyclophosphate,and analyzed the possible causes by literature review.RESULTS The adverse reaction was likely to be caused of adenosine cyclophosphate,and the possible reasons may be related to the patient’s own disease,compatibility and excipients.CONCLUSION Adenosine cyclophosphate is widely used in clinic and with high safety,but it can also cause serious adverse reactions of anaphylactic shock,so it shall be used with caution.
作者
郭媛媛
张弋
GUO Yuanyuan;ZHANG Yi(Department of Pharmacy,Tianjin First Central Hospital,Tianjin 300192,China)
出处
《中国现代应用药学》
CAS
CSCD
北大核心
2020年第15期1889-1890,共2页
Chinese Journal of Modern Applied Pharmacy
关键词
环磷腺苷
不良反应
过敏性休克
adenosine cyclophosphate
adverse reaction
anaphylactic shock