摘要
目的探讨慢性阻塞性肺病(COPD)患者在风险概率明确下的风险决策认知功能。方法采用风险概率明确的骰子博弈试验(GDT)对34例COPD患者(COPD组)和与其人口资料学相匹配的30例健康对照组(HC组)进行风险决策能力测试,同时采用词汇流畅性、数字广度等认知功能测验进行背景认知功能测试。结果在GDT中,与HC组(8.09±6.65)分比较,COPD组(12.67±3.11)分更倾向于选择风险选项(F=-3.594,P=0.001);与COPD组(23.30±30.73)分比较,HC组(58.46±34.14)分更倾向于在输钱后暂时选择安全选项,两组负反馈利用率差异有统计学意义(F=-4.122,P<0.001);与HC组掷骰子最终总资产为正数(966.67±2785.60)元比较,COPD组(-1623.53±4121.57)元的最终总资产为负数,差异有统计学意义(F=-2.975,P=0.004)。结论COPD患者存在广泛认知功能损害,风险决策功能也显著下降,并与负反馈利用率相关。
Objective To explore the decision-making function under clear risk condition in patients with chronic obstructive pulmonary Disease(COPD).Methods Game of dice task(GDT)with clear risk probability was used to test the risk decision-making ability of 34 patients with COPD(COPD group)and 30 healthy control(HC group)matched with their demographic data.At the same time,the background cognitive functions such as verbal fluency test,digit span test were detected.Results Within the Game of Dice Test,the COPD group(12.67±3.11)was more likely to choose the risk option(F=-3.594,P=0.001)than the HC group(8.09±6.65).Compared with the COPD group(23.30±30.73),the HC group(58.46±34.14)was more likely to choose the safety option temporarily after losing money,and the difference of negative feedback utilization rate between the two groups was statistically significant(F=-4.122,P<0.001).The final total assets of the COPD group(-1623.53±4121.57)were usually negative,while those of the HC group(966.67±2785.60)were all profitable,with a statistically significant difference(F=-2.975,P=0.004).Conclusion Cognitive decline was observed in patients with COPD,and significant changes were observed in decision-making ability under clear risk probability,which was associated with negative feedback utilization.
作者
吕志
江银玲
胡盼盼
王璐
范晓云
杨万春
Lü Zhi;Jiang Yinling;Hu Panpan(Dept of Pulmonary,The Second People's Hospital of Hefei,Hefei 230011;Dept of Geriatric Respiratory and Critical Care Medicine,The First Affiliated Hospital of Anhui Medical University,Hefei 230022;Dept of Neurology,The First Affiliated Hospital of Anhui Medical University,Hefei 230022)
出处
《安徽医科大学学报》
CAS
北大核心
2020年第8期1246-1250,共5页
Acta Universitatis Medicinalis Anhui
基金
国家重点研发计划(编号:2018YFC1314200)
安徽省2017年公益性技术应用研究联动计划项目(编号:1704f0804030)。
关键词
慢性阻塞性肺病
风险决策
负反馈利用率
认知
chronic obstructive pulmonary disease
decision making
negative feedback utilization
cognition
