摘要
目的研究急性心肌梗死临床治疗中选择麝香保心丸联合阿托伐他汀的效果。方法以2018年4月—2019年4月该院收治的急性心肌梗死共82例患者为对象,随机数字表法分为2组,其中接受阿托伐他汀治疗的41例患者视作对照组,接受麝香保心丸联合阿托伐他汀治疗的41例患者视作观察组,比较两组总有效率、炎症因子水平、心功能变化情况。结果观察组治疗后炎症因子hs-CRP、IL-6水平为(3.16±1.53)mg/L、(4.33±1.52)ng/L,低于对照组(5.10±1.58)mg/L、(7.64±1.75)ng/L,差异有统计学意义(t=5.648、9.144,P<0.05);观察组治疗后心功能指标LVEDV、LVESV、LVEF水平均优于对照组,差异有统计学意义(P<0.05);观察组治疗后并发症发生率为12.20%,低于对照组发生率31.71%,差异有统计学意义(P<0.05)。结论麝香保心丸联合阿托伐他汀治疗急性心肌梗死能够更明显降低炎症水平,改善患者内皮功能以及心功能。
Objective To study the effect of choosing Shexiang Baoxin Pill combined with atorvastatin in the clinical treatment of acute myocardial infarction. Methods A total of 82 patients with acute myocardial infarction admitted to the hospital from April 2018 to April 2019 were selected. The random number table method was used to divide the patients into 2 groups. Among them, 41 patients receiving atorvastatin were regarded as control group, and 41 patients receiving Shexiang Baoxin Pill combined with atorvastatin were regarded as observation group. The total effective rate,the level of inflammatory factors and the changes of heart function were compared between the two groups. Results The levels of inflammatory factors hs-CRP and IL-6 in the observation group after treatment were(3.16 ±1.53) mg/L and(4.33±1.52)ng/L, which were lower than those in the control group(5.10±1.58) mg/L and(7.64±1.75)ng/L,the difference was statistically significant(t =5.648, 9.144, P <0.05);heart function indexes LVEDV, LVESV, and LVEF of the observation group after treatment were better than those of the control group,the difference was statistically significant(P<0.05);the incidence of complications after treatment in the observation group 12.20%, lower than the control group incidence rate of 31.71%,the difference was statistically significant(P <0.05). Conclusion Shexiang Baoxin Pills combined with atorvastatin in the treatment of acute myocardial infarction can significantly reduce the inflammation level, improve the endothelial function and cardiac function of patients.
作者
白雄
BAI Xiong(Department of Cardiology,Xinxin Hospital,Xianyang,Shanxi Province,713200 China)
出处
《系统医学》
2020年第12期66-68,共3页
Systems Medicine
关键词
急性心肌梗死
麝香保心丸
阿托伐他汀
治疗
心功能
炎症水平
Acute myocardial infarction
Shexiang Baoxin Pill
Atorvastatin
Treatment
Heart function
Inflammation level
