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持续性与间歇性肠内营养支持对非糖尿病重型颅脑创伤患者血糖及不良反应发生率的影响

Effect of Continuous and Intermittent Enteral Nutrition Support on Blood Glucose and Incidence of Adverse Reactions in Non-diabetic Patients with Severe Craniocerebral Trauma
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摘要 目的:探讨持续性与间歇性肠内营养支持对非糖尿病重型颅脑创伤患者血糖及不良反应发生率的影响。方法:选取2017年6月-2019年12月笔者所在医院收治的非糖尿病重型颅脑创伤患者60例,按照随机数字法分为对照组(采用持续性肠内营养支持)和观察组(采用间歇性肠内营养支持),每组30例。比较两组空腹血糖及不良反应情况。结果:观察组治疗第7天血糖水平低于对照组(P<0.05);观察组反流发生率为6.67%,误吸发生率为6.67%,腹泻发生率为10.00%,均低于对照组的30.00%、26.67%、36.67%,差异均有统计学意义(P<0.05);观察组腹胀发生率为23.33%,便秘发生率为10.00%,均低于对照组的30.00%、20.00%,但差异均无统计学意义(P>0.05)。结论:将间歇性肠内营养支持应用于非糖尿病重型颅脑创伤患者中能够改善空腹血糖水平,不良反应发生率低,值得临床推广。 Objective:To investigate the effect of continuous and intermittent enteral nutrition support on blood glucose and incidence of adverse reactions in non-diabetic patients with severe craniocerebral trauma.Method:A total of 60 non-diabetic patients with severe craniocerebral trauma treated in our hospital from June 2017 to December 2019 were selected and divided into the control group(using continuous enteral nutrition support)and the observation group(using intermittent enteral nutrition support)according to random number method,with 30 cases in each group.Fasting blood glucose and adverse reactions were compared between the two groups.Result:The blood glucose level in the observation group on the 7th day of treatment was lower than that of the control group(P<0.05).In the observation group,the incidence of reflux was 6.67%,the incidence of aspiration was 6.67%,and the incidence of diarrhea was 10.00%,which were lower than 30.00%,26.67%,36.67%of the control group,and the differences were statistically significant(P<0.05).The incidence of abdominal distension was 23.33%,and the incidence of constipation was 10.00%in the observation group,which were lower than 30.00%,20.00%of the control group,but the differences were not statistically significant(P>0.05).Conclusion:Intermittent enteral nutrition support can improve fasting blood glucose level in non-diabetic patients with severe craniocerebral trauma,with low incidence of adverse reactions,which is worthy of clinical promotion.
作者 莫琴 邱剑远 林艳霞 麦小燕 MO Qin;QIU Jianyuan;LIN Yanxia;MAI Xiaoyan(Shiyan People’s Hospital,Bao’an District,Shenzhen City,Shenzhen 518108,China;不详)
出处 《中外医学研究》 2020年第23期135-137,共3页 CHINESE AND FOREIGN MEDICAL RESEARCH
关键词 非糖尿病重型颅脑创伤 肠内营养 间歇性 持续性 Non-diabetic patients with severe craniocerebral trauma Enteral nutrition Intermittent Continuous
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