摘要
目的:研究阿奇霉素不同疗程用药对治疗小儿肺炎支原体肺炎临床疗效及安全性的影响。方法:选择2017年2月—2018年2月期间我院收治的86例小儿肺炎支原体肺炎患者,并随机平均分为对照组和试验组,每组43例。两组都采用阿奇霉素治疗,对照组5d一个疗程,试验组7d一个疗程,分别进行4个疗程,对比两组患者的退热时间、肺部啰音消失时间、咳嗽消失时间、X线片消失时间、住院时间以及不良反应发生率。结果:两组患者退热时间差异无统计学意义(P>0.05),但试验组肺部啰音消失时间、咳嗽消失时间、X线片消失时间以及住院时间分别显著短于对照组,差异有统计学意义(P<0.05);两组患者不良反应发生率差异无统计学意义(P>0.05)。结论:静脉滴注7d阿奇霉素能够显著缩短临床病症的时间以及住院时间,提高疗效。
Objective:To study the effect of different treatments of azithromycin on the clinical efficacy and safety of children with pneumonia mycoplasma pneumonia.Methods:Eighty-six patients with pediatric pneumoniae pneumonia admitted to our hospital from February 2017 to February 2018 were randomly divided into control group and experimental group,with 43 cases in each group.The two groups were treated with azithromycin.The control group took 5 days as a course of treatment,and the test group used 7 days as a course of treatment for 4 courses.The antipyretic time,the disappearance time of the lungs,and the cough were compared between the two groups.Disappearance time,disappearance time of X-ray film,hospitalization time,and incidence of adverse reactions.Results:There was no significant difference in the time of fever between the two groups (P>0.05).However,the disappearance time of lung voice,disappearance time of cough,disappearance time of X-ray film and hospitalization time were significantly shorter in the experimental group than in the control group (P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05).Conclusion:In summary,intravenous infusion of azithromycin for 7 days can significantly shorten the time of clinical disease and hospitalization time,improve the efficacy,and it is worth promoting.
作者
马洁
MA Jie(Children's Hospital Affiliated to Zhengzhou University,Zhengzhou Henan 450000,China)
出处
《药品评价》
CAS
2020年第12期13-14,34,共3页
Drug Evaluation
关键词
阿奇霉素
不同疗程
小儿肺炎支原体肺炎患者
临床疗效
Azithromycin
Different Courses of Treatment
Children with Mycoplasma Pneumoniae Pneumonia
Clinical Efficacy