摘要
目的了解2014-2018年玉溪市精神病医院住院病人艾滋病病毒(HIV)感染状况及其临床特征,为该人群艾滋病防治提供依据。方法采用回顾性研究方法,收集2014-2018年间玉溪市某精神病医院住院病人资料,包括人口学信息、临床指标和HIV感染状况,组间比较采用χ^2检验。结果12940名精神疾病病人HIV感染率为0.26%,而11445名未患精神疾病者HIV感染率为0.24%,差异无统计学意义(χ^2=0.078,P=0.779),35~44年龄段的女性精神病人HIV感染率为0.90%(12/1327),男性为0.20%(3/1476),差异有统计学意义(χ^2=4.031,P=0.031)。患有精神疾病的HIV感染者中,CD4+T淋巴细胞<200个/μL和CD4/CD8比值<0.5占比均高于未患精神疾病病人,差异均有统计学意义(χ^2=9.201,P=0.013和χ^2=18.240,P<0.001),流浪精神病人中梅毒感染、贫血者占比高于非流浪精神病人,差异有统计学意义(χ^2=4.507,P=0.023;χ^2=4.871,P=0.021)。结论中年女性精神病人HIV感染状况可能较男性更为严重,感染HIV的精神病人免疫状况较差,流浪精神病人更易出现营养不良和合并感染梅毒,需特别加以关注。
Objective To investigate the HIV serological status and clinical features of the hospitalized patients with mental disorder in Yuxi prefecture,Yunnan province between 2014 and 2018,to provide the strategies for prevention and treatment of the infectious diseases.Methods A retrospective observational study was conducted with a total of 24385 hospitalized patients in the second hospital of Yuxi.The information were collected including demographics,clinical indicators and HIV infection status,and comparison was made between the two groups by usingχ^2 test.Results The HIV infection rates were 0.26%among 12940 mentally ill patients and 0.24%among 11445 normal patients,with the difference not so statistically significant(χ^2=0.078,P=0.779).The HIV infection rates of 35-44 age group were 0.90%(12/1327)among mentally ill women and 0.20%(3/1476)among male patients,with the difference statistically significant(χ^2=4.031,P=0.031).The HIV infected patients with mental disorder had CD4+T lymphocyte cell counts<200 cell/μl and CD4/CD8 values<0.5,higher than the normal patients(χ^2=9.201,P=0.013 andχ^2=18.240,P<0.001).The co-infection rate of syphilis and HIV among homeless patients with mental disorder was higher than that with normal patients with mental disorder,with the difference statistically significant(χ^2=4.507,P=0.023).The ratio of anemia among homeless patients with HIV/AIDS and mental disorder was higher than that among those with normal mental disorder,with the difference statistically significant(χ^2=4.871,P=0.021).Conclusion The HIV infection status of the middle aged female patients with mental disorder may be worse than that of male patients.The mental disorder patients with HIV/AIDS have worse immunization status.The homeless mental disorder patients are more likely to suffer from malnutrition and co-infection with syphilis,which requires special attention.
作者
刘秀红
李世福
张志辉
董文斌
LIU Xiuhong;LI Shifu;ZHANG Zhihui;DONG Wenbin(The First Hospital of Yuxi,Yuxi 653100,Yunnan,China;Yuxi Prefecture Centre for Disease Control and Prevention,Yuxi 653100;The Second Hospital of Yuxi,Yuxi 653100)
出处
《中国艾滋病性病》
CAS
CSCD
北大核心
2020年第8期874-876,885,共4页
Chinese Journal of Aids & STD
关键词
艾滋病病毒
精神病
流浪精神病
感染率
临床特征
human immunodeficiency virus
mental disorder
homeless
infection rates
clinical feature
