摘要
目的评价甲基强的松龙联合硫酸镁治疗小儿毛细支气管炎的疗效。方法选取确诊毛细支气管炎病例78例,随机分为治疗组和对照组,两组均采用抗炎抗病毒、化痰、雾化吸入等综合治疗,治疗组在上述综合治疗基础上予以小剂量甲基强的松龙2mg/kg静脉滴注,每日一次,并连用25%硫酸镁25~40mg/kg静脉滴注,每日一次,连用三天。对照组给予地塞米松0.5mg/kg静脉滴注,每日一次。临床观察喘憋、咳嗽症状、肺部哮鸣音好转情况及其住院日,并观察不良反应发生情况。结果治疗组患儿在喘憋、咳嗽、肺部哮鸣音好转情况明显优于对照组,住院日缩短,经统计学检验,差异存在显著性(P<0.05).结论甲基强的松龙联合硫酸镁治疗小儿毛细支气管炎疗效显著。
Objective To evaluate curative effect of methylprednisolone combined with magnesium sulfate on pediatric bronchiolitis.Methods 78 cases confirmed with bronchiolitis were enrolled.They were randomly divided into treatment group and control group.Both groups were given anti-inflammatory,anti-virus,resolving phlegm,aerosol inhalation and other comprehensive treatment.On the basis of the above comprehensive treatment,treatment group was given small dose of methylprednisolone(2 mg/kg)for intravenous drip,once a day.And it was given 25%magnesium sulfate(25-40 mg/kg)for intravenous drip,once a day,lasting for three days.The control group was given0.5 mg/kg dexamethasone for intravenous drip,once a day.The recovery conditions of dyspnea,cough symptoms and lung wheezing rale,and hospitalization time were clinically observed.The occurrence of adverse reactions was observed.Results The recovery conditions of dyspnea,cough and lung wheezing rale in treatment group were significantly better than those in control group,and hospitalization time was shortened.Statistical test showed that differences were statistically significant(P<0.05).Conclusion The curative effect of methylprednisolone combined with magnesium sulfate is significant on pediatric bronchiolitis.
作者
陈小南
CHEN Xiao-nan(Department of Pediatrics,Third People's Hospital of Shaoguan,Shaoguan 512122,Guangdong Province,China)
出处
《罕少疾病杂志》
2020年第5期8-9,共2页
Journal of Rare and Uncommon Diseases
