摘要
目的探讨脓毒症有关中医现代文献中的证候分布特点。方法通过对中国知网(CNKI)、万方数据库、维普数据库、Medline等数据库中有关脓毒症中医现代文献进行检索,检索年限为1979年至2019年6月,对符合标准的文献进行阅读和摘录证候类型,参考《中医诊断学》《中医证候鉴别诊断学》《中医临床诊疗术语-证候部分》等著作中有关证候、证候要素的拆分方法进行对不规范和复合的证候类型进行规范和拆分,并提取病位类和病性类证候要素,使用描述性统计方法(频次/频率)进行统计分析。结果纳入156篇中医证候文献,涉及证候类型共78种,规范后证候类型共54种,录入证候的出现频次共1008次。出现频率大于5%的常见证候类型分别为热毒内盛证、瘀毒内阻证、火热炽盛证、腑气不通证、热毒血瘀证。规范后得到病位类证候要素6种,主要以脾、大肠、胃、肺为常见病位类证候要素(出现频率>10%)。病性类证候要素共有23种,出现频率>5%的依次为火(热)、毒(热、瘀、浊)、痰、气虚、血瘀、腑实,占总病性类证候要素的76.99%。结论脓毒症的证候纷繁复杂,发病初期证候类型以实证为主,气虚贯穿疾病发生发展过程,治疗过程中应重视脾胃功能的复原。
Objective:To explore the syndrome distribution characteristics of sepsis in modern TCM literature.Methods:Through the retrieval of the modern literature of CNKI,Wanfang database,VIP database,Medline and other databases,the retrieval period was from 1979 to June 2019,and the types of syndromes were read and extracted from the literature that met the inclusion criteria.Referring to the methods of splitting syndrome and syndrome elements in the works,the nonstandard and compound syndrome types were standardized and split,and the syndrome elements of disease location and disease nature were extracted,and the descriptive statistical method was used for statistical analysis.Results:156 TCM syndrome literature was included,involving 78 syndrome types,54 syndrome types after standardization,and 1008 times of entering syndrome frequency.The common syndrome types with frequency more than 5%were heat toxin internal excess syndrome,blood stasis and toxin internal resistance syndrome,fiery heat syndrome,Fu Qi stagnation syndrome and heat toxin blood stasis syndrome.After standardization,6 kinds of disease location syndrome elements were obtained,and spleen,large intestine,stomach and lung were the common disease location syndrome elements(frequency>10%).There were 23 kinds of disease type syndrome elements.The frequency of occurrence>5%was fire(heat),toxin(heat,blood stasis,turbidity),phlegm,Qi deficiency,blood stasis,Fu excess,accounting for 76.99%of the total disease type syndrome elements.Conclusion:The syndrome of sepsis is complex,and the syndrome type in the early stage of sepsis is mainly empirical.Qi deficiency runs through the occurrence and development of the disease,and attention should be paid to the recovery of spleen and stomach function in the treatment process.
作者
陈剑明
刘清泉
连博
王晓鹏
陈腾飞
黄坡
张瑞
王东东
徐霄龙
郭玉红
Chen Jianming;Liu Qingquan;Lian Bo;Wang Xiaopeng;Chen Tengfei;Huang Po;Zhang Rui;Wang Dongdong;Xu Xiaolong;Guo Yuhong(Beijing Traditional Chinese Medicine Hospital Affiliated to Capital Medical University,Beijing 100010,China)
出处
《中国中医急症》
2020年第8期1361-1364,1377,共5页
Journal of Emergency in Traditional Chinese Medicine
基金
国家自然科学基金项目(62041701,81673934,81973608)
国家“十三五”规划课题(2017ZX10305501)
北京市自然科学基金(7192083)
中国博士后面上基金(2019M650774)
首都医科大学校级自然科学基金(PYZ19174)
北京市属医院科研培育计划项目(PZ2019009)。
关键词
脓毒症
证候
证候要素
分布特点
文献研究
Sepsis
Syndrome
Syndrome elements
Distribution characteristics
Literature study
