摘要
目的:探讨匹伐他汀与阿托伐他汀分别联合丹参多酚酸盐对脑梗死患者血脂水平的影响。方法:回顾性收集我院2019年1月-2019年11月收治的88例脑梗死患者临床资料,将采用丹参多酚酸盐联合阿托伐他汀治疗的43例患者资料纳入A组,将采用丹参多酚酸盐联合匹伐他汀治疗的45例患者纳入B组,治疗1个月后,比较两组血脂水平、不良反应。结果:两组治疗后总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)水平均较治疗前低,且B组较A组低,差异有统计学意义(P<0.05);B组不良反应发生率较A组低,差异有统计学意义(P<0.05)。结论:匹伐他汀联合丹参多酚酸盐治疗效果较好,可有效调节脑梗死患者血脂水平,且安全性较好。
Objective:To investigate the effect of pitavastatin and atorvastatin combined with salvia miltiorrhiza polyphenolate on blood lipid levels in patients with cerebral infarction.Methods:The clinical data of 88 patients with cerebral infarction who were received by our hospital from January 2019 to November 2019 were retrospectively collected.The data of 43 patients who treated with salvia polyphenolate combined with atorvastatin were included in group A.45 patients who treated with salvia polyphenolate combined with pitavastatin were included in group B.After one month of treatment,the blood lipid levels and adverse reactions of the two groups were compared.Results:The total effective rate in group B was higher than that in group A,and the difference was statistically significant(P<0.05);compared the levels of TC,TG,LDL-C before treatment in the two groups,the difference was not statistically significant(P>0.05);The levels of TC,TG,LDL-C after treatment were lower than before treatment,and group B was lower than group A,the difference was statistically significant(P<0.05);the incidence of adverse reactions in group B was lower than group A,the difference was statistically significant(P<0.05).Conclusion:Pitavastatin combined with salvia miltiorrhiza polyphenolate has a better treatment effect,can effectively regulate the blood lipid level in patients with cerebral infarction,and has relatively better safety.
作者
刘艳芳
LIU Yan-fang(Department of Outpatient,Yimei General Hospital of Henan Province,Sanmenxia Henan 472300,China)
出处
《药品评价》
CAS
2020年第10期25-26,共2页
Drug Evaluation
关键词
脑梗死
匹伐他汀
阿托伐他汀
丹参多酚酸盐
血脂水平
Cerebral Infarction
Pitavastatin
Atorvastatin
Salvia Miltiorrhiza Polyphenolate
Blood Lipid Levels
