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急性大脑中动脉闭塞支架取栓术后平扫CT高密度征的临床研究 被引量:1

Clinical Study on Plain CT High-density Sign After Acute Middle Cerebral Artery Occlusion Stent Removal
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摘要 目的探讨急性大脑中动脉闭塞支架取栓术后平扫CT高密度征与患者的临床特征及远期预后的关系。方法回顾性纳入我院2015年8月至2019年10月连续登记的急性前循环大血管闭塞脑梗死并行机械取栓的患者,根据术后即刻平扫CT高密度征分为高密度征组和无高密度征组,分析比较两组临床基线资料,NIHSS评分(术后24小时及出院时),出血转化率,3月mRS评分及死亡率,并进行统计分析。结果纳入符合要求的110例患者,术后即刻平扫CT高密度征的76例,发生率69.1%。高密度征组溶栓比例高于无高密度征组(P<0.05),高密度征组DNT、OTP、穿刺到达到mTICI2b-3级时间、取栓次数均明显高于无高密度征组(P<0.05)。术后即刻平扫CT高密度征与死亡率、出血转化率、出院NIHSS评分、3月mRS评分有关(P<0.05)。结论急性大脑中动脉闭塞支架取栓后平扫CT高密度征可以预测患者临床转归与预后。 Objective To investigate the relationship between plain CT high-density sign after acute middle cerebral artery occlusion stent removal and clinical characteristics and long-term prognosis of patients.Methods Retrospectively enrolled patients who were continuously registered in our hospital from August 2015 to October 2019 for acute anterior circulation large vessel occlusion cerebral infarction and mechanical thrombectomy.According to plain CT high-density sign immediately after operation,they were divided into high-density sign group and non-high-density sign group.The clinical baseline data,NIHSS score(at 24 hours after surgery and discharge),bleeding conversion rate,mRS score at 3 months and mortality rate were analyzed and compared,and statistical analysis was performed.Results 110 eligible patients were included,and 76 patients had a high-density CT sign immediately after surgery that incidence was 69.1%.The thrombolysis rate in the high-density sign group was higher than that in the non-high-density sign group(P<0.05).DNT,OTP,puncture time to reach mTICI2b-3 grade and numbers of thrombectomy of high-density sign group were significantly higher than the non-high-density sign group(P<0.05).Immediate postoperative CT high-density signs were related to mortality,hemorrhage conversion rate,NIHSS score on discharge,and mRS score at 3 months(P<0.05).Conclusion Patients’clinical outcome and prognosis could be predicted by plain CT high-density sign after thrombectomy in acute middle cerebral artery occlusion。
作者 陈忠伦 都泓材 李肇坤 蒲明军 张杉杉 张献文 苏牟潇 Chen Zhonglun;Du Hongcai;Li Zhaokun(Department of Neurology,Mianyang Central Hospital,Mianyang,Sichuan 621000,China)
出处 《四川医学》 CAS 2020年第7期728-731,共4页 Sichuan Medical Journal
关键词 急性脑梗死 支架取栓 平扫CT高密度征 acute cerebral infarction stent thrombectomy plain CT high-density sign
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