摘要
目的探讨不同刚量的罗库溴铵对膝关节置换患者止血带反应和术后康复的影响。方法择期行单侧膝关节置换手术患者90例,年龄50~80岁,ASA分级Ⅰ~Ⅱ,随机分为3组,即罗库溴铵1.2mg/kg组(H组)、罗库溴铵0.6mg/kg组(L组)和生理盐水组(S组),3组患者均全身麻醉下接受超声引导下股神经阻滞。分别于出手术室时、术后24.48h记录患者的静息疼痛评分(VAS),于术后24.48h测量患者的大腿围度,术后记录患者的首次下床时间,近期(3天)和远期(3个月)并发症。结果H组和L组患者术后24、48h静息疼痛评分(VAS)低于S组(P<0.05),H组和1.组术后24.48h大腿围度变化值小于s组(P<0.05),H组L组患者术后首次下床时间明显早于S组(P<0.05)。结论静脉应用罗库溴铵可减轻患者术后疼痛,减轻止血带反应,縮短卧床时间。
Objective To investigate the effects of different doses of rocuronium on tourniquet related-reactions and postoperative rehabilitations in total knee arthroplasty.Methods A total of 90 patients aged 50-80 years,of ASA Ⅰ~Ⅱ scheduled for total knee arthroplasty were randomly allocated to 3 groups:rocuronium 1.2 mg/kg group,rocuronium 0.6 mg/kg group and saline group.All patients received ultrasound-guided femoral nerve block under general anesthesia.The resting Visual Analogue Scale(VAS)and thigh girth of patients was measured at 24h and 48h after surgery,and the leaving bed time,short-term complications(3 days after operation)and long-term complications(3 months after operation)were recorded.Results V AS in group H was lower than that in group S at 24h and 48h after operation(P<0.05).The increment of thigh girth at 24h and 48h after operation in group H and group L was smaller than that in group S(P<0.05).The leaving bed time in group H and group L was significantly earlier than in group S(P<0.05).Conclusion Intravenous use of rocuronium can reduce postoperative pain,reduce tourniquet-related reactions,and shorten the leaving bed time.
作者
陈慧
王溢文
周坤鹏
何莹
刘鹤
张月英
Chen Hui;Wang Yiwen;Zhou Kunpeng(Department of Anesthesiology,the Affiliated Hospital of Xuzhou Medical University,Jiangsu 221002,China)
出处
《医学研究杂志》
2020年第8期150-154,共5页
Journal of Medical Research
基金
江苏省徐州帀临床技术骨干研修计划项目(2018211006)。
关键词
罗库溴铵
膝关节置换
止血带相关反应
术后康复
Rocuronium
TKA
Tourniquet-related reactions
Postoperative rehabilitations
