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人体钩虫病流行现况与治疗进展 被引量:8

The prevalence of human hookworm disease and advances in its treatment
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摘要 钩虫呈全球性分布,其感染是引起贫血和营养不良的主要原因,是人类第二大寄生虫感染,多发生于热带、亚热带等发展中国家的贫困地区,为我国五大寄生虫病之一,是广泛流行于农村地区的土源性线虫病。据不完全统计,目前全世界钩虫感染者约达5~7亿,人群、牲畜较普遍易感,对人类危害甚大,能致使身体和智力发育迟缓,严重影响到人民群众的生命健康,是一个重大的健康问题。历经60多年的努力,我国在钩虫病的防治工作上取得了一系列令人瞩目的成就,除现有少数人体重要寄生虫病以外其余的已暂时被消灭。根据2017年全国土源性线虫感染监测分析显示:全国土源性线虫整体感染水平较低,为1.8%;钩虫感染率为1.0%,其中男性感染率为0.9%、女性感染率为1.1%;男性感染率明显低于女性(2=40.51,P<0.01);钩蚴检出率为3.2%,但仍存在高感染省份。通过及时查治病人及带虫者、提高个人及社会环境卫生水平、加强宣传防治知识、增强防病意识,避免感染。本文仅对目前钩虫病的流行现况、药物的治疗、防治策略进行了综述。 Hookworms are found globally,and hookworm infections are major cause of anemia and malnutrition.Hookworms are the second most widespread parasitic infection in human beings.Hookworm infections occurs in poor areas of tropical and subtropical developing countries and are one of the five major parasitic diseases in China.Hookworms are soil-transmitted helminths that are prevalent in rural areas.Statistics are incomplete,but about 500 to 700 million people around the world are infected with hookworms.People and livestock are generally susceptible to a hookworm infection,which is very harmful to human beings.It can cause physical and mental retardation and seriously affect people’s lives and health,making it a major health problem.After more than 60 years of effort,China has made a series of remarkable achievements in the prevention and control of hookworm disease.Although a few key human parasitic diseases remain,the rest have temporarily been eliminated.According to the monitoring and analysis of soil-transmitted helminths infections in China in 2017,the overall level of infection with soil-transmitted helminths is low(1.8%)in China.;The rate of hookworm infection was 1.0%,with rate of infection of 0.9%in males and 1.1%in females.The rate of infection in males was significantly lower than that in females(χ~2=40.51,P<0.01).The rate of detection of hookworm larvae was 3.2%,but the rate of detection is still high in some provinces.Infection can be avoided by a timely examination and treatment of patients and carriers,improvement of personal and public hygiene,and promotion of prevention knowledge and awareness.This paper reviews the current status of ancylostomiasis,drug treatments,and control strategies.
作者 白财福 杨亚明 BAI Cai-fu;YANG Ya-ming(School of Public Health,Kunming Medical University,Kunming 650000,China;Yunnan Institute of Parasitic Diseases)
出处 《中国病原生物学杂志》 CSCD 北大核心 2020年第7期865-868,F0003,共5页 Journal of Pathogen Biology
基金 国家自然科学基金项目(No.81660560)。
关键词 钩虫病 流行现况 药物治疗 防治策略 综述 hookworm disease prevalence drugtreatment control strategy review
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