摘要
目的观察改良1 470 nm半导体激光剜除术对良性前列腺增生患者尿流动力学及生存质量的影响。方法 2018年1月至2019年6月,良性前列腺增生患者150例,按照随机数字法分为观察组和对照组,对照组采取常规1 470nm半导体激光剜除术治疗;观察组采取改良1 470 nm半导体激光剜除术治疗,每组患者75例,记录两组围术期指标(手术时间、膀胱冲洗时间、留置膀胱造瘘管时间、留置导尿管时间、离床活动时间、住院时间)、尿流动力学(最大尿流率、残余尿量、最大膀胱容量)、生存质量评分、国际前列腺症状评分、血清电解质(钾、钠)、血红蛋白、并发症发生率进行对比。结果两组围术期指标无统计学差异(P>0. 05);术前两组尿流动力学、生存质量评分、国际前列腺症状评分无统计学差异(P>0. 05),术后均较本组术前显著改善,观察组各指标均优于对照组(P<0. 05);术前两组血清电解质、血红蛋白相比较,差异无统计学意义(P>0. 05);术后与术前相比较,差异无统计学意义(P>0. 05);观察组与对照组相比较,差异无统计学意义(P>0. 05);观察组并发症发生率小于对照组,差异具有统计学意义(P<0. 05)。结论改良1 470 nm半导体激光剜除术有助于进一步提高良性前列腺增生患者尿流动力学及生存质量并降低术后并发症发生率,值得推广。
Objective To observe the effect of modified 1 470 nm semiconductor laser ablation on urodynamics and quality of life of patients with benign prostatic hyperplasia.Methods Totally 150 patients with benign prostatic hyperplasia treated from Jan.2018 to Jun.2019 were selected and randomly divided into two groups:the control group(conventional 1 470 nm semiconductor laser enucleation group) and observation group(modified 1 470 nm semiconductor laser enucleation group).The perioperative indicators(lengths of operation,bladder irrigation,indwelling cystostomy tube applicantion,indwelling urinary catheter usage,bedtime activity and hospitalization),urodynamics(maximum urinary flow rate,residual urine volume and maximum bladder volume),quality of life score,international prostate symptom score,serum electrolytes(potassium and sodium),hemoglobin and incidence of complications of the two groups were compared.Results The differences in perioperative indicators between the two groups were not significant(P> 0.05).Before the surgery,none of the differences between the two groups in urodynamics,quality of life score and international prostate symptom score was significant(P>0.05).Despite of the fact that all the indicators of both groups made a remarkable improvement after the surgery,the indicators in the observation group were all better than those in the control group,which was statistically significant(P<0.05).There was no statistical difference in serum electrolytes and hemoglobin between the two groups before the surgery(p>0.05).The difference of each group in serum electrolytes and hemoglobin was not obvious before and after the surgery(P>0.05).No significant difference in serum electrolytes and hemoglobin was found between the two groups after the surgery(P>0.05).The incidence of complications in the observation group was less than that in the control group,which was statistically significant(P <0.05).Conclusions Improved 1 470 nm semiconductor laser ablation is helpful for further improve ment of the urodynamics and q
作者
郭小勇
陈晓峰
邓旺龙
王栋
GUO Xiao-yong;CHEN Xiao-feng;DENG Wang-long;WANG Dong(Department of Urology,Chenzhou First People's Hospital,Chenzhou 423000,China)
出处
《中国激光医学杂志》
CAS
2020年第3期144-149,共6页
Chinese Journal of Laser Medicine & Surgery