摘要
目的:观察中医特色护理干预对化疗治疗NSCLC的毒副反应影响。方法:选择我院2017年3月~2019年1月收治的94例患者,依据患者意愿半随机将94例患者匹配成53例观察组与41例对照组,分别予以常规护理^+中医特色护理干预和常规护理。记录两组护理期间出现的毒副反应;对比分析两组干预前后免疫功能变化及生活质量评分。结果:毒副反应发生率对比:观察组32.08%显著低于对照组51.60%(P<0.05);免疫功能对比:观察组干预后CD3^+、CD4^+、CD4^+/CD8^+均较对照组低,CD8^+较对照组高(P<0.05);生活质量评分对比:观察组干预后WHOQOL-100量表各维度评分皆高于对照组(P<0.05)。结论:中医特色护理干预可降低化疗治疗NSCLC的毒副反应,对患者免疫功能及生活质量均有一定改善作用,具有临床借鉴价值。
Objective:To observe the effect of traditional Chinese medicine(TCM)special nursing intervention on toxic and side effects for NSCLC chemotherapy.Methods:A total of 94 patients who were admitted to the hospital from March 2017 to January 2019 were enrolled.According to patients'willingness,they were semi-randomly divided into observation group(53 cases)and controlled group(41 cases).The two groups were given routine nursing combined with TCM special nursing intervention or routine nursing,respectively.The toxic and side effects during nursing period in both groups were recorded.The immune function changes and quality of life scores before and after intervention were compared between the two groups.Results:The incidence of toxic and side effects in the observation group was significantly lower than that in the controlled group(32.08%vs 51.60%)(P<0.05).Comparison of immune function:After intervention,CD3^+,CD4^+ and CD4^+/CD8^+ in the observation group were lower than those in the controlled group,while CD8^+ was higher than that in the controlled group(P<0.05).Comparison of quality of life scores:After intervention,scores of WHOQOL-100 scale in all dimensions in the observation group were higher than those in the controlled group(P<0.05).Conclusion:TCM special nursing intervention can reduce toxic and side effects of NSCLC chemotherapy,which can improve immune function and quality of life,and is of clinical reference value.
作者
程清
郭蕾
严思又
彭丽
黄美玲
沈琳
蔡伦华
CHENG Qing;GUO Lei;YAN Siyou(Department of Oncology,Sichuan Provincial Cancer Hospital,Chengdu Sichuan 610041,China;Career Development Department,Sichuan Provincial Cancer Hospital,Chengdu Sichuan 610041,China)
出处
《四川中医》
2020年第7期208-211,共4页
Journal of Sichuan of Traditional Chinese Medicine
关键词
中医特色护理
非小细胞
毒副反应
免疫功能
生活质量
Traditional Chinese medicine special nursing
Non-small cell
Toxic and side effect
Immune function
Quality of life
