摘要
研究了5种中草药复合醇提取物和含有该5种中草药复合醇提物的祛痘精华液的安全性和功效性,用痤疮丙酸杆菌进行体外抑菌实验;用脂多糖LPS诱导RAW264.7小鼠巨噬细胞建立的炎症模型,进行抗炎功效测试;同时用红细胞溶血测试进行刺激性评估;最后通过含有该5种中草药复合提取物的祛痘精华液进行人体斑贴安全性测试及祛痘功效测试并与市售某款含1%水杨酸有效成分的热销祛痘产品进行对比。结果显示含有此5种中草药复合醇提物的祛痘精华液安全、温和且具有祛痘抗炎作用。
The safety and efficacy of the extract from the mixture of 5 kinds of Chinese herbal medicines and the acne care essence containing this extract were studied.In vitro bacteriostasis experiment was conducted using the acne propionibacterium.Inflammatory model of with lipopolysaccharide(LPS)-induced RAW264.7 mice macrophage was set up for the anti-inflammatory efficacy test.Irritation was evaluated by RBC hemolysis test.Finally,the acne care essence containing the extract from the mixtrue of five kinds of Chinese herbal medicines was evaluated in the aspects of safety(human body patch test)and acne efficacytest,and it was also compared with a best-selling acne care product containing the active ingredient of 1%salicylic acid.The results showed that the acne care essence containing the extract from the mixtrue of five kinds of Chinese herbal medicines was safe and mild and had anti-acne effect.
作者
刘婷
刘芳
陈亮
龚盛昭
LIU Ting;LIU Fang;CHEN Liang;GONG Sheng-zhao(Guangzhou UniAsia Cosmetic Technology Co.,Ltd.,Guangzhou,Guangdong 510663,China;Guangdong Industry Technical College,Guangzhou,Guangdong 510300,China)
出处
《日用化学工业》
CAS
CSCD
北大核心
2020年第8期553-559,565,共8页
China Surfactant Detergent & Cosmetics
关键词
中草药
祛痘精华
安全性
功效性
化妆品
Chinese herbal medicine
acne care essence
safety
efficacy
cosmetic
