摘要
多囊卵巢综合征(PCOS)是育龄期女性最常见的内分泌疾病之一,也是引起女性不孕的重要原因之一,以高雄激素血症和排卵障碍为临床特点。由于PCOS的病因复杂,至今尚无明确的发病机制。在PCOS患者体内,一些炎症因子的水平显著高于健康妇女,由此推断,PCOS的发生可能与慢性炎症有一定的相关性。除此之外,PCOS的炎症状态可能与子宫内膜癌、心血管疾病等一些预后较差的疾病密切相关。因此,本文就炎症因子与PCOS的相关性做一综述,为探究PCOS的病因及发病机制提供一定线索,为PCOS的预防及治疗提供新的思路。
Polycystic ovary syndrome(PCOS)is one of the most common endocrine diseases affecting women of childbearing age,which is also one of the important reasons causing infertility,and it is characterized by hyper-androgenism and ovulation disorder in clinical practice.Due to the complex etiology of PCOS,there is no clear pathogenesis.In patients with PCOS,the levels of some inflammatory factors are significantly higher than those in healthy women.It is inferred that the occurrence of PCOS may be related to chronic inflammation.In addition,the inflammatory status of PCOS may be closely related to some diseases with poor prognosis such as endometrial cancer and cardiovascular disease.Therefore,the paper makes a review in terms of the correlation between inflammatory factors and PCOS.It provides clues for the study of etiology and pathogenesis as well as the new way for the prevention and treatment of PCOS.
作者
高晴
张爱萍
刘阿慧
张学红
GAO Qing;ZHANG Ai-ping;LIU A-hui;ZHANG Xue-hong(The First Clinical Medical College of Lanzhou University,Lanzhou 730000;The Reproductive Medicine Special Hospital of the 1st hospital of Lanzhou University,Lanzhou 730000;The First Hospital of Lanzhou University,Lanzhou 730000;Key Laboratory for Reproductive Medicine&Embryo,Gansu Province,Lanzhou 730000)
出处
《生殖医学杂志》
CAS
2020年第8期1100-1104,共5页
Journal of Reproductive Medicine
关键词
多囊卵巢综合征
炎症因子
慢性炎症
微粒
Polycystic ovary syndrome
Inflammatory factors
Chronic inflammation
Microparticles
