摘要
目的探讨血清淀粉样蛋白A (SAA)在急性附睾炎中的诊断价值。方法选取2018年3月至2019年9月商洛市中心医院收治的67例拟诊断为急性附睾炎患者(急性附睾炎组)作为研究对象,另选取同期在该院体检健康成年男性58例作为对照组,两组SAA、血白细胞计数(WBC)、尿WBC及C-反应蛋白(CRP)水平进行检测并比较各指标水平及其阳性率,分析SAA与CRP、血WBC及尿WBC相关性,利用受试者工作特征曲线(ROC曲线)分析SAA对急性附睾炎的诊断效能,以及比较急性附睾炎组治疗前及治疗7d后各指标水平。结果急性附睾炎组SAA、CRP、血WBC及尿WBC水平与对照组比较,差异均有统计学意义(P<0.05)。急性附睾炎组SAA与CRP、血WBC及尿WBC水平呈正相关(r=0.792、0.816、0.429,P<0.05)。急性附睾炎组SAA、CRP、血WBC及尿WBC的阳性率分别92.54%、74.17%、85.33%和61.49%。以SAA为变量绘制急性附睾炎的ROC曲线,ROC曲线下面积为0.932(P<0.05),95%可信区间为0.915~0.948。急性附睾炎治疗前SAA、CRP及血WBC水平与其治疗7d后各指标水平比较,均明显下降,差异有统计学意义(P<0.05)。结论SAA检测对急性附睾炎患者的诊断具有重要应用价值。
Objective To explore the diagnostic value of serum amyloid protein A(SAA)in the diagnosis of acute epididymitis.Methods From March 2018 to September 2019,67 patients(acute epididymitis group)admitted to Shangluo Central Hospital were selected as study subjects.In addition,58 healthy adult males who had physical examination in a hospital during the same period were selected as the control group.SAA,blood white blood cell count(WBC),urine WBC and C-reactive protein(CRP)levels of the two groups were detected and the levels of each indicator and their positive rates were compared.The correlation between SAA and CRP,blood WBC and urine WBC was analyzed,and the diagnostic efficacy of SAA in acute epididymitis was analyzed using receiver operating characteristic curve(ROC curve),and the levels of each indicator were compared before and 7 days after treatment in the acute epididymitis group.Results The levels of SAA,CRP,blood WBC and urine WBC in the acute epididymitis group were significantly different from those in the control group(P<0.05).SAA was positively correlated with CRP,blood WBC and urine WBC levels in the acute epididymitis group(r=0.792,0.816,0.429,P<0.05).The positive rates of SAA,CRP,blood WBC and urine WBC in the acute epididymitis group were 92.54%,74.17%,85.33%and 61.49%,respectively.The ROC curve of acute epididymitis was drawn with SAA as the variable.The area under the ROC curve was 0.932(P<0.05)and the 95%confidence interval was 0.915—0.948.The levels of SAA,CRP and blood WBC before treatment of acute epididymitis were significantly decreased compared with those 7 days after treatment,with statistically significant differences(P<0.05).Conclusion SAA test has important application value in the diagnosis of acute epididymitis.
作者
赵璇
李可
茹伯战
ZHAO Xuan;LI Ke;RU Bozhan(The Second Affiliated Hospital of Xi′an Jiaotong University,Xi′an,Shaanxi 710004,China;Department of Clinical Laboratory,Shangluo Central Hospital,Shangluo,Shaanxi 726000,China)
出处
《检验医学与临床》
CAS
2020年第16期2344-2346,2349,共4页
Laboratory Medicine and Clinic
关键词
急性附睾炎
血清淀粉样蛋白
C-反应蛋白
白细胞计数
acute epididymitis
serum amyloid protein A
C-reactive protein
white blood cell count
