摘要
目的探讨原发性高血压患者血清钠钾比及24h尿钠钾比与血压节律之间的关系。方法回顾性分析2017年9月至2019年5月原发性高血压患者264例,根据患者24h动态监测血压情况,分为杓型血压组(夜间血压下降率≥10%)159例及非杓型血压组105例(夜间血压下降率<10%)。各组血清钠钾比及24h尿钠钾比等指标进行比较分析。结果两组患者的男性占比、年龄、体质量指数(BMI)、同型半胱氨酸、空腹血糖、冠心病患病率比较,差异有统计学意义(P<0.05);经患者年龄、性别、BMI校正后,非杓型血压组的血清钠水平、血清钠钾比、24h尿钠钾比、血清钾水平与杓型血压组比较,差异有统计学意义(P<0.05)。结论原发性高血压患者应及时调整钠、钾摄入,选择适合的降压药物及给药方法,有助于血压降低。
Objective To investigate the relationship between serum sodium-potassium ratio and 24 h urinary sodium-potassium ratio and blood pressure rhythm in patients with essential hypertension.Methods A retrospective analysis of 264 consecutive patients with essential hypertension from September 2017 to May 2019 was performed.According to the 24 h dynamic monitoring of patients′blood pressure,159 cases were divided into arytenoid blood pressure group(nocturnal blood pressure reduction rate≥10%)and 105 cases were divided into non-arytenoid blood pressure group(nocturnal blood pressure reduction rate<10%).Serum sodium-potassium ratio and 24 h urinary sodium-potassium ratio and other indicators in each group were compared and analyzed.Results There were statistically significant differences between the two groups in the prevalence of male proportion,age,body mass index(BMI),homocysteine,fasting blood glucose,and coronary atherosclerotic heart disease,the difference was statistically significant(P<0.05).After adjustment for age,sex and BMI,the serum sodium level,serum sodium-potassium ratio,24 h urinary sodium-potassium ratio and serum potassium level of the non-arytenoid blood pressure group were compared with that of the arytenoid blood pressure group,with statistically significant differences(P<0.05).Conclusion Patients with essential hypertension should adjust sodium and potassium intake in time,choose appropriate antihypertensive drugs and administration methods,and help lower blood pressure.
作者
郭钰
朱丽娜
张丽华
GUO Yu;ZHU Lina;ZHANG Lihua(Department of Cardiovascular Medicine,the Second Affiliated Hospital of Zhengzhou University,Zhengzhou,Henan 450014,China)
出处
《检验医学与临床》
CAS
2020年第16期2337-2339,2343,共4页
Laboratory Medicine and Clinic
关键词
血清钠钾比
24h尿钠钾比
原发性高血压
血压节律
serum sodium-potassium ratio
24 h urinary sodium-potassium ratio
essential hypertension
blood pressure rhythm
