摘要
目的研究阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)患者耳鸣的发生情况,并探讨耳鸣发生的可能相关因素。方法研究对象为通过夜间多导睡眠图(PSG)监测检查诊断为OSAHS的79例患者,进行耳科检查、听力检查、耳鸣病史采集及偏头痛问卷调查,根据睡眠中呼吸暂停低通气指数(AHI)分组,比较各组间耳鸣的发生率及各组间年龄、BMI、最低血氧、平均听阈(PTA)的差异。再根据有无耳鸣进行分组,分析年龄、BMI、最低血氧、PTA、偏头痛、头晕、胃食管反流等因素与耳鸣的相关性。结果79例OSAHS患者中,有46例(58.2%)有不同程度听力下降,主要为4000-8000Hz频率阈值升高的高频听力下降,按AHI分组,各组间各频率阈值无统计学差异(P>0.05)。耳鸣的发生率为43.0%(34/79),根据AHI分组:轻度OSAHS(AHI 5-15),中度OSAHS(AHI 15-30),重度OSAHS(AHI>30),其耳鸣的发生率分别为66.7%,42.1%,35.6%,各组间无统计学差异(P>0.05)。根据有无耳鸣分组,耳鸣的发生与年龄、BMI、最低血氧、REM睡眠时间、PTA、偏头痛、头晕、胃食管反流等因素无明显相关性。结论OSAHS患者可能更易损伤高频听力,OSAHS患者耳鸣的发生率与其严重程度无明显相关性。OSAHS患者耳鸣的发生可能是多种因素共同作用的结果。
Objective To study the incidence of tinnitus in patients with obstructive sleep apnea hypopnea syndrome,and to explore the relevant factors.Methods The subjects of the study were 79 patients diagnosed with OSAHS through night polysomnography(PSG)monitoring examinations.All patients had taken the otology examination and pure tone audiometry.They were interviewed by the investigators who were trained together,using the same questionnaire.All patients were divided into groups according to apnea hypopnea index,the incidence of tinnitus,age,BMI,minimum blood oxygen and average hearing threshold were compared among groups.Patients were further divided into tinnitus and no tinnitus groups.The correlation of age,BMI,minimum blood oxygen,PTA,migraine,dizziness and gastroesophageal reflux was compared between the two groups in tinnitus occurrence.Results Among 79 patients with OSAHS,46(58.2%)had different degrees of hearing loss,mainly high-frequency hearing loss with increased 4000-8000Hz frequency threshold.Grouped by AHI,there was no significant difference in each frequency threshold between the groups(P>0.05).The incidence of tinnitus was 43.0%(34/79).Grouped by AHI:mild OSAHS(AHI5-15),moderate OSAHS(AHI15-30),severe OSAHS(AHI>30),the incidence of tinnitus was 66.7%,42.1%,35.6%,respectively.There was no significant difference(P>0.05).According to the groups with and without tinnitus,the occurrence of tinnitus had no obvious correlation with factors such as age,BMI,minimum blood oxygen,REM sleep time,PTA,migraine,dizziness,gastroesophageal reflux.Conclusion OSAHS patients may be more susceptible to high-frequency hearing damage,and the incidence of tinnitus in OSAHS patients was not significantly correlated with its severity.The occurrence of tinnitus in OSAHS patients may be the result of a combination of many factors.
作者
王琳
刘菊
余力生
马鑫
WANG Lin;LIU Ju;YU Lisheng;MA Xin(Department of Otolaryngology,Peking University People’s Hospital,Beijing 100044,China;Department of Otolaryngology,Ordos Central Hospital,Inner Mongolia)
出处
《中华耳科学杂志》
CSCD
北大核心
2020年第4期744-748,共5页
Chinese Journal of Otology
