摘要
目的探究预测甲状腺乳头状癌预后的因素。方法以"甲状腺乳头状癌预后""甲状腺乳头状癌超声检查""甲状腺乳头状癌与桥本甲状腺炎"和"甲状腺乳头状癌相关基因"为检索词进行文献检索,对现阶段发现的可以用于预测甲状腺乳头状癌预后的因素如患者的一般特征、原发灶的超声特征、血清学指标、相关基因的突变等做一综述。结果存在病灶直径大于1 cm、腺外浸润等超声特征和相关基因突变等因素,患者术后复发风险升高;合并桥本氏甲状腺炎的患者可能有更好的预后。结论目前有诸多因素在一定程度上都可以预测患者的复发风险,但基本都处于研究阶段,因此要提高生存率还得依靠更规范的术后随访管理。
Objective To explore the factors that predict the prognosis of papillary thyroid carcinoma.Method The literature searching terms include"prognosis of papillary thyroid carcinoma""ultrasound of papillary thyroid carcinoma""papillary thyroid carcinoma and Hashimoto's thyroiditis",and"genes related to papillary thyroid carcinoma".The factors used to predict the prognosis of papillary thyroid carcinoma such as the patient's clinical characteristics,ultrasound characteristics,serological indicators,genes mutations,etc.were reviewed.Results Ultrasound features such as lesion diameter greater than 1 cm,extra-glandular invasion,and related gene mutations may increase the risk of postoperative recurrence.Patients with Hashimoto's thyroiditis may have better prognosis.Conclusion There are many factors that can predict the risk of recurrence in patients to a certain extent,but most of them are just in the study,so it is necessary to enact more standardized follow-up management to improve the survival rate.
作者
周余
程若川
ZHOU Yu;CHENG Ruochuan(Department of Thyroid Surgery,the First Affiliated Hospital of Kunming Medical University,Kunming 650032,R.P.China)
出处
《中国普外基础与临床杂志》
CAS
2020年第8期1028-1032,共5页
Chinese Journal of Bases and Clinics In General Surgery
基金
云南省基础研究计划(昆医联合专项)[项目编号:2018FE001(–168)]。
关键词
甲状腺乳头状癌
预后
预测因素
综述
papillary thyroid carcinoma
prognosis
predictive factor
review
