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艰难梭菌感染实验室诊断方法的研究进展 被引量:1

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摘要 艰难梭菌是存在于人体肠道中的一种专性厌氧革兰阳性芽孢杆菌,系条件致病菌,可引起从轻微腹泻到致命的伪膜性结肠炎等轻重不等的临床症状。艰难梭菌感染(Clostridioides difficile infection,CDI)的发病率和死亡率在全球范围内不断增高,特别是北美地区027型高产毒力菌株造成的医院内暴发流行,引起了世界范围的广泛关注。CDI的诊断主要依据临床表现和实验室检查,在缺乏患者相应的临床症状时,CDI实验室诊断显得尤为重要。本文作者从艰难梭菌的厌氧培养、免疫分析和核酸扩增等实验室诊断方法的研究进展进行综述,为CDI的早期诊断和治疗提供新思路。
作者 吴伶俐 李楣
出处 《东南大学学报(医学版)》 CAS 2020年第3期403-406,共4页 Journal of Southeast University(Medical Science Edition)
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