摘要
目的分析对比剂不同注射速率(碘普罗胺300mgI/ml)在低剂量CTPA成像中应用的可行性。方法纳入60例临床疑似肺动脉栓塞拟行CTPA检查的患者,随机数字表法分为A、B、C三组,每组各20例,A组注射速率为5ml/s,对比剂用量35ml,延迟时间采用团注测试法(bolus test);B、C两组注射速率分别为4ml/s、3.5ml/s,对比剂用量25ml,延迟时间采用团注追踪(bolus tracking)技术。三组均采用管电压80kV、固定毫安秒80mAs,iDose43级迭代重建算法重建。分别测量肺动脉主干及分支的CT值并计算其平均值,对三组图像的肺动脉平均CT值、信噪比(SNR)、对比噪声比(CNR)、主观图像质量评价、有效剂量(ED)等进行比较分析。结果随着注射速率的降低,三组图像肺动脉平均CT值依次降低,但肺动脉CT值均高于300HU,能满足临床诊断需要,且肺动脉平均CT值、SNR、CNR、ED、主观图像质量评价相比差异均无统计学意义(P>0.05)。结论采用3.5ml/s注射速率,25ml的对比剂用量,肺动脉CTPA低剂量成像质量不仅能满足诊断需要,而且降低了碘摄入量和碘流率(iodine delivery rate,IDR),有效地减少对比剂肾病及对比剂外渗风险,值得推广应用。
Objective To analyze the feasibility of using different injection rates of contrast medium(iopramide 300 mgI/ml)in low dose CTPA imaging.Methods Sixty patients with suspected pulmonary embolism were randomly divided into three groups group A(n=20),group B(n=20)and group C(n=20).The injection rate of group A was 5 ml/s,the dosage of contrast agent was 35 ml,the injection rate of bolus test;group B and group C was 4 ml/s and 3.5 ml/s respectively,the dosage of contrast agent was 25 ml,and the delay time was bolus tracking.All three groups were reconstructed with tube voltage of 80 kV,fixed mAs of 80 mAs and iDose43 iterative reconstruction algorithm.The CT values of the trunk and branches of pulmonary artery were measured and their average values were calculated.The average CT value of pulmonary artery,signal-to-noise ratio(SNR),contrast-to-noise ratio(CNR),subjective image quality evaluation and effective dose(ED)of the three groups of images were compared and analyzed.Results With the decrease of injection rate,the average CT value of pulmonary artery in the three groups decreased in turn,but the CT value of pulmonary artery was higher than 300 HU,which could meet the needs of clinical diagnosis.There was no significant difference in the average CT value of pulmonary artery,SNR,CNR,ED and subjective image quality evaluation(P>0.05).Conclusion Using 3.5 ml/s injection rate,contrast agent dosage of 25 ml and low dose imaging quality of pulmonary artery CTPA can not only meet the needs of diagnosis,but also reduce iodine intake and iodine flow rate(Iodine Delivery Rate,IDR),and the risk of contrast nephropathy and contrast agent extravasation,which is worth popularizing.
作者
王甜
刘铁军
曹治婷
廖玉荣
廖立
黄婉
莫亮
WANG Tian;LIU Tiejun;CAO Zhiting;LIAO Yurong;LIAO Li;HUANG Wan;MO Liang(Department of Radiology, Liuzhou People's Hospital, Guangxi Zhuang Autonomous Region, Liuzhou 545006, P.R.China)
出处
《医学影像学杂志》
2020年第7期1190-1193,共4页
Journal of Medical Imaging
基金
广西壮族自治区卫计委自筹经费科研课题(编号:Z20170651)。
