摘要
脑脊液通过前颅窝颅骨及硬脑膜的缺损进入鼻腔或鼻窦,形成脑脊液鼻漏。脑脊液鼻漏按其病因可分为创伤性、医源性、肿瘤源性及自发性4种。其中自发性脑脊液鼻漏(spontaneous cerebrospinal fluid rhinorrhea,SCSFR)是一种原因不明的非创伤性脑脊液鼻漏,因其起病隐匿在临床上少见。临床症状多表现为单侧清水样鼻漏,常因特定头位加重脑脊液的流出,可无其他合并症,因此易被误诊、漏诊。
Cerebrospinal fluid(CSF) rhinorrhea is the result of an abnormal communication between sinonasal tract and the subarachnoid space through skull base defect. The etiology of CSF rhinorrhea can be traumatic, iatrogenic, tumor induced and spontaneous. Spontaneous CSF rhinorrhea(SCSFR) occurs in the absence of trauma, surgery, or other inducing events. SCSFR is rarely encountered in daily clinical practice, thus misdiagnosis is common when the clinical symptoms are atypical. SCSFR does not typically self-resolve and requires surgical repair. Timely and effective closure of defects is critical to avoid potentially serious consequences including brain abscess and meningitis. Clinical research indicated an underestimation of SCSFR in the past. Nowadays, with the improvement of diagnostic techniques and clinical awareness, the detection rate of SCSFR has increased. This study conducted a systematic review about the etiology and treatment strategy of SCSFR.
作者
朱正洁
程岚
杨军
ZHU Zhengjie;CHENG Lan;YANG Jun
出处
《临床耳鼻咽喉头颈外科杂志》
CAS
北大核心
2020年第6期573-576,共4页
Journal of Clinical Otorhinolaryngology Head And Neck Surgery
关键词
脑脊液鼻漏
发病机制
治疗
cerebrospinal fluid rhinorrhea
etiology
therapy
