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探讨血液透析超滤缓解重度肾病性水肿的临床效果及预后 被引量:1

Exploration of the clinical effect and prognosis of hemodialysis ultrafiltration to relieve severe nephrotic edema
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摘要 目的 :探讨与分析血液透析超滤缓解重度肾病性水肿的临床效果及预后。方法 :选择80例重度肾病性水肿患者为观察研究对象,将患者分为对照组(行常规方式治疗)和研究组(行血液透析超滤治疗)各40例,对比分析两组患者的临床疗效。结果 :研究组中血白蛋白、血肌酐、尿素氮、尿蛋白、N-乙酰基-β-D-氨基葡萄糖苷酶、尿肾脏损伤分子-1、体质量水平较对照组更低,而尿量水平、不良症状缓解率更高(P<0.05)。结论 :血液透析超滤缓解重度肾病性水肿效果显著,能够有效改善重度肾病性水肿症状和预后。 Objective: To explore and analyze the clinical effect and prognosis of hemodialysis ultrafiltration on relief of severe nephrotic edema. Methods: Eighty patients with severe nephrotic edema were selected as the subjects and divided into a control group(routine treatment) and a study group(hemodialysis ultrafiltration treatment) with 40 cases each. The clinical effects were compared between the two groups and analyzed. Results: The levels of serum albumin and creatinine, urea nitrogen, urine protein, urinary N-acetyl-β-D-glucosaminidase, urinary kidney injury molecule-1 and body weight were significantly lower while the urinary volume and the remission rate of adverse symptoms were significantly higher in the study group than the control group(P<0.05). Conclusion: Hemodialysis ultrafiltration has a significant effect on relief of severe nephrotic edema and can effectively improve its symptoms and prognosis.
作者 赵晓琴 ZHAO Xiaoqin(Hemodialysis Room,the Central Hospital of Sanmenxia City,He’nan Sanmenxia 472000,China)
出处 《上海医药》 CAS 2020年第15期54-57,79,共5页 Shanghai Medical & Pharmaceutical Journal
关键词 血液透析超滤 重度肾病性水肿 预后 hemodialysis ultrafiltration severe nephrotic edema prognosis
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