摘要
目的分析与评价腹腔镜袖状胃切除术(laparascopic sleeve gastrectomy,LSG)治疗代谢综合征的临床疗效。方法2017年6月~2018年6月我院收治的代谢综合征病人52例,均接受LSG并完成定期随访,记录并比较术前及术后的体重、体质指数(BMI)、额外体重减轻率、腰围、颈围、血脂代谢、血糖代谢、部分生化指标的变化情况及代谢合并症的改善情况。结果52例病人均完成12个月的定期随访,术后12个月体重、BMI分别由(123.92±21.03)kg、(42.98±6.70)kg/m^2、降到(80.13±10.35)kg、(27.66±3.30)kg/m^2;空腹血糖、糖化血红蛋白分别由(6.64±1.95)mmol/L、(6.67±1.55)%降到(4.17±0.56)mmol/L、(1.07±0.30)、(5.15±0.21)%;甘油三酯、低密度脂蛋白胆固醇分别由(2.47±0.72)mmol/L、(3.03±0.71)mmol/L降到(1.20±0.18)mmol/L、(2.05±0.48)mmol/L,与术前比较差异均有统计学意义(P<0.05);术后12个月大部分病人的代谢综合征及其合并症得到不同程度的改善和(或)治愈。结论LSG治疗代谢综合征安全、可靠、疗效显著,不仅明显减轻体重而且还能改善或治愈其合并症。
Objective To analyze and evaluate the efficacy of laparoscopic sleeve gastrectomy(LSG)in the treatment of metabolic syndrome.Methods The clinical data of 52 patients with metabolic syndrome who underwent LSG and completed regular follow-up in our hospital from June 2017 to June 2018,We recorded and compared the measurements of preoperation and postoperation,including:body weight,BMI,excess weight loss rate,waist、neck circumferences,blood lipid metabolism,blood glucose metabolism,changes in some biochemical indicators and improvement of comorbidities.Results 52 patients have complished regular follow up in 12 months after surgery,body weight,BMI decreased from(123.92±21.03)kg、(42.98±6.70)kg/m^2 to(80.13±10.35)kg、(27.66±3.30)kg/m^2 in 12 months after surgery,fasting blood glucose,glycosylated hemoglobin decreased from(6.64±1.95)mmol/L、(6.67±1.55)%to(4.17±0.56)mmol/L、(5.15±0.21)%.Triglyceride,low-density lipoprotein cholesterol decreased from(2.47±0.72)mmol/L、(3.03±0.71)mmol/L to(1.20±0.18)mmol/L、(2.05±0.48)mmol/L,the differences were statistically significant(P<0.05).Most patients with metabolic syndrome and related comorbidities have been improved and/or cured after surgery in 12 months.Conclusion LSG treatment of metabolic syndrome is safe,not only significantly reduce body weight but also improves or heals the metabolic syndrome and related comorbidities.
出处
《临床外科杂志》
2020年第6期564-567,共4页
Journal of Clinical Surgery
基金
新疆维吾尔自治区引进高层次人才天池百人计划资助项目(201939)。
关键词
腹腔镜袖状胃切除术
代谢综合征
合并症
疗效
laparascopic sleeve gastrectomy
metabolic syndrome
comorbidity
efficacy
