摘要
目的对联合筋膜鞘悬吊术与额肌瓣悬吊术矫正先天性中重度上睑下垂的临床疗效进行对比.方法检索了中英文数据库,中文数据库有万方、维普、中国知网和中国生物医学.英文数据库有Cochrane图书馆、PUBMED和Web of Science网站等.时间为自数据库建库以来至2020年5月各数据库所收录的文摘.收集了联合筋膜鞘悬吊术(CFS)与额肌瓣悬吊术矫正先天性中重度上睑下垂术后疗效比较的病例对照研究,严格根据制订的纳入和排除标准筛选文章,选出文章进行治疗评价,确定结局指标并进行数据提取.进行Meta分析所采用的软件是Review Manager 5.3和state 14.0软件.结果共选取了11篇文章,其中296例患者(381眼)为观察组,均采用联合筋膜鞘悬吊术(CFS),291例患者(379眼)为对照组,均采用的是额肌瓣悬吊术.Meta分析结果显示观察组与对照组患者术后矫正率对比的(OR=2.9495%CI:1.94,4.47);术后并发症发生率对比的(OR=0.17,95%CI:0.11,0.27);术后6个月上睑回退量分析结果显示,(WMD=-0.5,95%CI:-0.53,-0.47),结局指标差异均具有统计学意义(P<0.05).结论两种术式治疗上睑下垂疗效都是比较满意的,联合筋膜鞘悬吊术术后矫正率优于额肌瓣悬吊术,且联合筋膜鞘悬吊术后并发症发生率与上睑回退量均低于额肌悬吊术,更为安全,值得在临床上应用并推广.
Objective To compare the Efficacy of conjoint fascial sheath suspension and frontalis muscle flap suspension in the correction of moderate and severe congenital blepharoptosis.Methods Seven databases including Wanfang,VIP,CNKI,Chinese Medical Literature,Public Medical Literature,Science Network and Cochrane Library were searched independently.The randomized or non-randomized controlled trials for comparing conjoint fascial sheath suspension and frontalis muscle flap suspension in the treatment of congenital moderate and severe blepharoptosis were collected.The selection of documents and the extraction of data are based on inclusion and exclusion criteria.The quality of the study was assessed by the Newcastle-Ottawa scale.The meta-analysis of primary outcomes was performed by Review Manager 5.3 and Stata14.0.Results A total of 11 clinical trials were involved in this study,including 587 patients(760 eyes).Conjoint fascial sheath suspension was performed in the experimental group and frontalis muscle flap suspension was performed in the control group.The OR value of postoperative correction rate between the 2 groups was 2.94(95%CI:1.94,4.47),the incidence rate of complications was 0.17(95%CI:0.11,0.27).The WMD value of the amount of upper eyelid retraction at 6 months after operation was-0.5(95%CI:-0.53,-0.47).All differences were statistically significant(P<0.05).Conclusion Both conjoint fascial sheath suspension and frontalis muscle flap suspension achieved satisfactory results in the treatment of congenital moderate and severe blepharoptosis.However,conjoint fascial sheath suspension was safer and more reliable,and the postoperative correction was high.Therefore,conjoint fascial sheath suspension was the better method to popularize in clinic.
作者
费蒙辉
艾江
牛梓晗
马少林
FEI Meng-hui;AI Jiang;NIU Zi-han;MA Shao-lin(Department of Plastic Surgery,the First Affiliated Hospital,Xinjiang Medical University,Xinjiang Uygur Autonomous Region,830000,China)
出处
《中国医疗美容》
2020年第7期40-45,共6页
China Medical Cosmetology
关键词
上睑下垂
额肌瓣悬吊术
联合筋膜鞘悬吊术
META分析
Blepharoptosis
Frontalis muscle flap suspension
conjoint fascial sheath suspension
Meta-analysis
