摘要
目的:总结34例浅表型基底细胞癌(BCC)患者的临床表现、皮肤镜及组织病理特点。方法:对2009年1月—2017年12月该院皮肤科门诊确诊的34例浅表型BCC患者临床表现、皮肤镜与皮损组织病理资料进行回顾性分析。结果:34例患者中男14例,女20例,以老年人居多,皮损最好发于躯干。32例皮损表现为单发性红斑、斑片及糜烂,2例为多发皮损。皮肤镜下皮损部位主要表现为枫叶样结构及轮辐状区域。皮损组织病理表现为真皮内芽蕾样嗜碱性细胞团块,与表皮相连,沿水平方向延伸、生长;边缘细胞呈栅栏状排列,可见周边裂隙。大部分患者真皮浅层可见淋巴细胞浸润(85.3%)、肿瘤团块内色素沉积(67.6%)及周边纤维组织增生(76.5%)。结论:浅表型BCC的临床表现、皮肤镜及组织病理特点均与经典型BCC相异,临床医生需提高对该病的认识以减少误诊。
Objective: To summarize the clinical, dermatoscopic and pathological features of superficial basal cell carcinoma(BCC). Methods: They retrospectively analyzed the clinical data of 34 patients diagnosed with superficial BCC in Chongqing First People’s Hospital from January 2009 to December 2017. Results: Among the 34 cases(14 males and 20 females), most were elderly patients. The lesions were most commonly seen in the trunk. Thirty-two cases presented with a solitary macule, patch or erosion, and the other two cases with multiple lesions. Dermatoscopy showed maple leaf-like structure and spoke-shaped areas.Histopathology revealed basophilic bud-shaped tumors formed by horizontal extension of cutaneous ridge into dermis, together with peripheral palisades and fissures between the tumor and the surrounding interstitial substance. Most cases showed lymphocytes infiltration in dermis(85.3%), pigmentation of tumor(67.6%), and hyperplasia of interstitial fibrous tissues(76.5%). Conclusion:The clinical manifestations, dermoscopy and histopathological characteristics of superficial BCC are different from those of classic BCC.It is important for clinicians to improve their understanding of superficial BCC to reduce misdiagnosis.
作者
冯林
余音
张颖
卢阳
史丙俊
江阳
FENG Lin;YU Yin;ZHANG Ying;LU Yang;SHI Bing-jun;JIANG Yang(Department of Dermatology,Chongqing Hospital of Traditional Chinese Medicine,Chongqing 400011,China)
出处
《临床皮肤科杂志》
CAS
CSCD
北大核心
2020年第7期394-397,共4页
Journal of Clinical Dermatology
关键词
基底细胞癌
浅表型
临床表现
皮肤镜
组织病理
basal cell carcinoma,superficial
clinical manifestation
dermatoscopic feature
histopathological changes
