摘要
目的探讨Ti O2纳米管的制备及表面碘负载后的结构表征。方法利用电化学阳极氧化法制备Ti O2纳米管,扫描电镜观察纳米管形态;采用电沉积法进行碘负载,扫描电镜下观察其形貌,X射线荧光光谱元素分析,半定量测定元素含量。结果制得Ti O2纳米管,管径100~200 nm,管长0.1~1μm,纳米管形态规整;在纳米管上进行电沉泳积法负载碘,扫描电镜下可见纳米管上颗粒状含碘聚合物,X射线荧光光谱分析I元素含量为4.114%,存在形式为离子或共价结合。结论利用电化学阳极氧化法制备的纳米管形态均一,管长、管径适宜,比表面积大,可作为负载药物的优良载体。电沉积法载碘经电镜扫描观测表征、X射线荧光光谱元素分析、半定量测定证明了碘的成功负载。
Objective To explore the preparation of titanium nanotubes, and the characterization of nanotubes contained iodine. Methods The anodic oxidation method was used to prepare the TiO2 nanotubes, and the electrodeposition method to load iodine on the nanotubes. Observing the morphology of TiO2 nanotubes under scanning electron microscope, X-ray fluorescence spectral element analysis, semi-quantitative determination of element content. Results With the diameter of about 100-200 nm and the length about 1 μm, the nanotubes were prepared by the 24 h anodic oxidation presenting a regular shape;Scanned by electron microscope, the nanotubes loaded with iodine by electrodeposition method had polymer particulate iodine on the surface. The amount of iodine was about 4.114%, iodine existed in the form of ionic or covalently bound.Conclusion Electrochemical anodic oxidation method is a simple and scientific method which can produce nanotubes with uniform configuration. The nanotubes anodizing for 24 h after has a suitable length and diameter, which can be used as an excellent drug load carrier. The successful load of iodine is proved by the X-ray fluorescence spectroscopy elemental analysis,semi-quantitative determination and analyzed by X-ray fluorescence spectroscopy.
作者
肖杰
王万明
黄少斌
XIAO Jie;WANG Wan-ming;HUANG Shao-bin(Department of Orthopedics,900th Hospital of the Joint Logistics Support Unit of the PLA,Fuzhou,Fujian 350025,China)
出处
《中国骨与关节损伤杂志》
2020年第7期700-702,共3页
Chinese Journal of Bone and Joint Injury
基金
福建省自然科学基金(2014J01369)
后勤重大项目合作项目(AWS16J032)。
